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Cheap Flights from Panama City (PTYA) to Rome (ROME)

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Flight deals from Panama City to Rome

Looking for a cheap last-minute deal or the best return flight from Panama City to Rome? If you want to travel next month, return fares start from $1,176. Find the lowest prices on one-way and return tickets right here.
Rome.$1,176 per passenger.Departing Sun, 2 Aug, returning Wed, 19 Aug.Return flight with Air France and KLM.Outbound indirect flight with Air France, departs from Panama City Tocumen International on Sun, 2 Aug, arriving in Rome Fiumicino.Inbound indirect flight with KLM, departs from Rome Fiumicino on Wed, 19 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,176, select.
Rome.$1,180 per passenger.Departing Tue, 28 Jul, returning Mon, 7 Sep.Return flight with Air France and KLM.Outbound indirect flight with Air France, departs from Panama City Tocumen International on Tue, 28 Jul, arriving in Rome Fiumicino.Inbound indirect flight with KLM, departs from Rome Fiumicino on Mon, 7 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,180, select.
Rome.$1,199 per passenger.Departing Thu, 21 Jan, returning Wed, 10 Feb.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Thu, 21 Jan, arriving in Rome Fiumicino.Inbound indirect flight with Turkish Airlines, departs from Rome Fiumicino on Wed, 10 Feb, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,199, select.
Rome.$1,200 per passenger.Departing Fri, 5 Feb, returning Mon, 15 Feb.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Fri, 5 Feb, arriving in Rome Fiumicino.Inbound indirect flight with Turkish Airlines, departs from Rome Fiumicino on Mon, 15 Feb, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,200, select.
Rome.$1,201 per passenger.Departing Wed, 14 Oct, returning Thu, 22 Oct.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Wed, 14 Oct, arriving in Rome Fiumicino.Inbound indirect flight with Turkish Airlines, departs from Rome Fiumicino on Thu, 22 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,201, select.
Rome.$1,201 per passenger.Departing Mon, 30 Nov, returning Mon, 7 Dec.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Mon, 30 Nov, arriving in Rome Fiumicino.Inbound indirect flight with Turkish Airlines, departs from Rome Fiumicino on Mon, 7 Dec, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,201, select.
Rome.$1,201 per passenger.Departing Fri, 30 Oct, returning Sun, 15 Nov.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Fri, 30 Oct, arriving in Rome Fiumicino.Inbound indirect flight with Turkish Airlines, departs from Rome Fiumicino on Sun, 15 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,201, select.
Rome.$1,201 per passenger.Departing Fri, 27 Nov, returning Sun, 31 Jan.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Fri, 27 Nov, arriving in Rome Fiumicino.Inbound indirect flight with Turkish Airlines, departs from Rome Fiumicino on Sun, 31 Jan, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,201, select.
Rome.$1,203 per passenger.Departing Mon, 28 Sep, returning Fri, 2 Oct.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Mon, 28 Sep, arriving in Rome Fiumicino.Inbound indirect flight with Turkish Airlines, departs from Rome Fiumicino on Fri, 2 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,203, select.
Rome.$1,204 per passenger.Departing Mon, 2 Nov, returning Tue, 17 Nov.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Mon, 2 Nov, arriving in Rome Fiumicino.Inbound indirect flight with Turkish Airlines, departs from Rome Fiumicino on Tue, 17 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,204, select.
Rome.$1,218 per passenger.Departing Thu, 22 Apr, returning Mon, 24 May.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Thu, 22 Apr, arriving in Rome Fiumicino.Inbound indirect flight with Air Europa, departs from Rome Fiumicino on Mon, 24 May, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,218, select.
Rome.$1,233 per passenger.Departing Mon, 14 Sep, returning Mon, 28 Sep.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Mon, 14 Sep, arriving in Rome Fiumicino.Inbound indirect flight with Turkish Airlines, departs from Rome Fiumicino on Mon, 28 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,233, select.
Rome.$1,234 per passenger.Departing Mon, 24 May, returning Sat, 29 May.Return flight with KLM.Outbound indirect flight with KLM, departs from Panama City Tocumen International on Mon, 24 May, arriving in Rome Fiumicino.Inbound indirect flight with KLM, departs from Rome Fiumicino on Sat, 29 May, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,234, select.
Rome.$1,235 per passenger.Departing Tue, 13 Apr, returning Thu, 22 Apr.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Tue, 13 Apr, arriving in Rome Fiumicino.Inbound indirect flight with Air Europa, departs from Rome Fiumicino on Thu, 22 Apr, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,235, select.
Rome.$1,243 per passenger.Departing Tue, 28 Jul, returning Wed, 19 Aug.Return flight with Air France and KLM.Outbound indirect flight with Air France, departs from Panama City Tocumen International on Tue, 28 Jul, arriving in Rome Fiumicino.Inbound indirect flight with KLM, departs from Rome Fiumicino on Wed, 19 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,243, select.
Rome.$1,264 per passenger.Departing Sun, 9 Aug, returning Tue, 8 Sep.Return flight with Air France.Outbound indirect flight with Air France, departs from Panama City Tocumen International on Sun, 9 Aug, arriving in Rome Fiumicino.Inbound indirect flight with Air France, departs from Rome Fiumicino on Tue, 8 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,264, select.

Find the cheapest month to fly from Panama City to Rome

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Rome flights are currently cheapest in August.
Jul
from $1,471
Aug
from $1,176
Sep
from $1,233
Oct
from $1,201
Nov
from $1,204
Dec
from $1,375
Jan
from $1,401
Feb
from $1,200
Mar
from $1,327
Apr
from $1,235
May
from $1,234
Jun
from $1,284

Alternative Panama City to Rome routes

Looking for the cheapest, fastest or easiest route from Panama City to Rome? You could fly into the following airports instead.

Rome Ciampino

13km from central Rome
Closest
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Rome Fiumicino

23km from central Rome
Cheapest
from $1,176
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Panama City to Rome: Flight information

The things to know before you go.
Cheapest flight found$1,176
Cheapest month to flyAugust

Finding cheap flights from Panama City to Rome: Frequently asked questions

There are 2 airports in Rome: Rome Ciampino and Rome Fiumicino.
The best price we found for a return flight from Panama City to Rome is $1,176. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Panama City to Rome. But we found flights with one or more stops from $1,176.
As of July 2026, there are no flights flying from Panama City to Rome.
The cheapest month to fly from Panama City to Rome is usually August.
If you're flying from Panama City, the cheapest airport near Rome is Rome Fiumicino – which is 22.9 km away from the centre of Rome. We've found flights into this airport from $1,176.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Rome on Sunday, 2 August 2026.
No airlines currently offer direct flights between Panama City and Rome. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Rome but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Rome is around 40 days in advance, so don’t leave your flight to the last minute.

In July, the average temperature is usually around 25°C. August is typically the warmest month in Rome, when it usually averages around 30°C. You can expect the least rain in July. The coldest month is January, with temperatures averaging 5°C. The rainiest month is November.
The cheapest airline that flies to Rome is Air France .

Travelling from Panama City to Rome: what you need to know

  • Panama City has a couple of airports where you can kick off your travels. Explore your options for reserving a flight from Panama City to Rome departing from Panama City Tocumen International Airport (PTY) or Balboa Airport (BLB).

  • When landing in Rome, Rome Fiumicino Airport (FCO) and Rome Ciampino Airport (CIA) are the major entry points.

  • Rome is six hours ahead of Panama City and observes the UTC+1 timezone.

  • Leave enough time to catch your Panama City to Rome flight. As a general rule, turn up at least two hours before international departures and an hour ahead for domestic flights.

  • Flying during a popular month such as July? School holidays and other popular seasons can mean longer lines and delays at security. Be extra cautious and arrive up to four hours before international flights and two hours before a domestic departure.

How to find the cheapest flights from Panama City to Rome

  • To find cheap Panama City to Rome flights, book ahead. Airlines typically offer their most competitively priced fares when flights first go on sale.

  • Finding cheap plane tickets from Panama City to Rome is more likely if you're flexible with your travel dates. Use the 'Whole month' function to see the lowest prices across the month and land a fantastic deal.

  • Snapping up a cheap flight from Panama City to Rome couldn't be easier with Price Alerts. All you need to do is set up one of these automatic alerts and we'll notify you as soon as there's a better deal.

  • Select your ideal departure and arrival times, airlines and number of stops by using the filters. Or sort your Panama City to Rome flight results by 'Best,' 'Cheapest' or 'Fastest.'

Flying from Panama City

Panama City Tocumen International Airport (PTY)

  • Think about adding a stopover to potentially find a cheaper Panama City to Rome flight. Simply deselect 'Direct flights only' when searching for departures from Panama City Tocumen International Airport. Take a pause at one of these popular options:

    • Madrid Airport (MAD)

    • New York Newark Airport (EWR)

    • Washington Dulles Airport (IAD)

  • Located around 18 kilometres from the centre of Panama City, PTY can be reached in about 35 minutes by car (depending on traffic). The journey by public transport takes roughly 50 minutes.

  • Need a handy hotel near Panama City Tocumen International Airport? If you're catching an early flight from Panama City to Rome, these stays will have you moments from your departure lounge:

  • 88% of flights leaving Panama City Tocumen International Airport arrive at their destination according to schedule. Given its strong performance rating, you're unlikely to experience delays when taking off from PTY.

Balboa Airport (BLB)

  • BLB is about 5 kilometres from central Panama City. It'll take 10 minutes or so to get to the airport in a car from the city centre. Public transport takes roughly 20 minutes.

  • Start your holiday sooner with an additional night away from home. Before your flight from Panama City to Rome, kick back in one of these hotels near Balboa Airport:

  • Flights from Balboa Airport are known for their punctuality, with 88% of them touching down as expected.

Arriving in Rome

Rome Fiumicino Airport (FCO)

  • Rome Fiumicino Airport (FCO) is approximately 23 kilometres from the centre of Rome. If you're catching a taxi or a ride-share, the drive will take around 40 minutes.

  • It typically takes 30 minutes to get there when travelling by public transport.

  • Reserve a hotel near FCO if you're coming in on a late flight from Panama City to Rome. Settle into one of these options and skip the long transfer:

  • Pick up a Rome Fiumicino Airport rental car and discover Rome and beyond with your own set of wheels. Surprice, RentSmart24 and Noleggiare are top outlets to choose from here.

  • For the best deal, book your ride from Rome Fiumicino Airport about three weeks ahead of your Panama City to Rome flight.

Rome Ciampino Airport (CIA)

  • Rome Ciampino Airport (CIA) is roughly 14 kilometres from the centre of Rome. Once you've hopped off your flight from Panama City to Rome, it takes approximately 20 minutes to reach the heart of the city in a ride-share or taxi.

  • If you hop on public transport, the ride to the centre takes 20 minutes or so.

  • After your flight from Panama City to Rome, unwind at a hotel near CIA. These are some comfortable options that'll help you get into relaxation mode:

  • No need to worry about public transport schedules or slow-moving taxi lines. Pick up a Rome Ciampino Airport rental car and let your trip unfold on your terms. Compare offers from RentSmart24, Sicily by Car and Surprice.

  • Get the pick of the lot. Booking your ride from CIA one week in advance often means better prices and a bigger choice of vehicles.

Best time to go to Rome

  • It's time to work out your trip dates for your flight from Panama City to Rome. August is the most popular month for a trip to Rome. If you like a more low-key vibe, go in March.

  • The warmest month in Rome is August, with temperatures ranging between 20ºC (68ºF) and 33ºC (91ºF). Lock in your Panama City to Rome ticket then if that's your idea of comfortable weather.

  • January sees average temperatures of between 2ºC (36ºF) and 14ºC (57ºF). Look for cheap flights from Panama City to Rome around that time if you like cooler conditions.

More about Rome

  • When it comes to looking for somewhere to lay your head, you'll find the top stays in Rome right here. Check out these hotels once you've locked in your flight from Panama City to Rome:

  • Every great adventure has to include some sightseeing. Vatican Museums, St. Peter's Basilica and Vatican Hill are must-visits when exploring Rome.

Explore more of Italy

  • Rome has loads to offer, but there are so many other parts of Italy waiting to be discovered. About 483 kilometres northwest of Rome, a trip to Milan will fill your itinerary to the brim. Start with leading attractions like Leonardo's Last Supper Museum, Teatro alla Scala and Milan Cathedral.

  • If you're interested in discovering another well-known destination in Italy, head for Naples, about 193 kilometres southeast of Rome. Piazza del Plebiscito, Naples National Archaeological Museum and San Carlo Theatre are key highlights.

Plan smart, explore more

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Prices shown on this page are estimated lowest prices only. Found in the last 12 days.