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Cheap Flights from Melbourne (MLB) to Knoxville (TYS)

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      Travellers and cabin class, 1 Adult, Economy

      Compare Melbourne Orlando International to Knoxville flight deals

      Find the cheapest month or even day of the year to fly to Knoxville

      Book the best Knoxville fare with no extra fees

      Flight deals from Melbourne Orlando International to Knoxville

      Looking for a cheap last-minute deal or the best return flight from Melbourne Orlando International Airport to Knoxville Airport? If you want to travel next month, return fares start from $613. Find the lowest prices on one-way and return tickets right here.
      Knoxville.$446 per passenger.Departing Mon, 23 Nov, returning Fri, 27 Nov.Return flight with Delta.Outbound indirect flight with Delta, departs from Melbourne Orlando International on Mon, 23 Nov, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Fri, 27 Nov, arriving in Melbourne Orlando International.Price includes taxes and charges.From $446, select.
      Knoxville.$608 per passenger.Departing Tue, 29 Sep, returning Mon, 5 Oct.Return flight with Delta.Outbound indirect flight with Delta, departs from Melbourne Orlando International on Tue, 29 Sep, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Mon, 5 Oct, arriving in Melbourne Orlando International.Price includes taxes and charges.From $608, select.
      Knoxville.$613 per passenger.Departing Fri, 2 Oct, returning Thu, 8 Oct.Return flight with Delta.Outbound indirect flight with Delta, departs from Melbourne Orlando International on Fri, 2 Oct, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Thu, 8 Oct, arriving in Melbourne Orlando International.Price includes taxes and charges.From $613, select.
      Knoxville.$716 per passenger.Departing Sat, 19 Sep, returning Wed, 23 Sep.Return flight with Delta.Outbound indirect flight with Delta, departs from Melbourne Orlando International on Sat, 19 Sep, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Wed, 23 Sep, arriving in Melbourne Orlando International.Price includes taxes and charges.From $716, select.
      Knoxville.$731 per passenger.Departing Fri, 21 May, returning Sun, 23 May.Return flight with Delta.Outbound indirect flight with Delta, departs from Melbourne Orlando International on Fri, 21 May, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Sun, 23 May, arriving in Melbourne Orlando International.Price includes taxes and charges.From $731, select.

      Find the cheapest month to fly from Melbourne Orlando International to Knoxville

      We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Melbourne Orlando International to Knoxville flights are currently cheapest in November.
      Sep
      from $716
      Oct
      from $613
      Nov
      from $446
      Dec
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      Jan
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      Feb
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      Mar
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      Apr
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      May
      from $731
      Jun
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      Jul
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      Aug
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      Melbourne Orlando International to Knoxville: Alternative routes

      Compare routes from Melbourne Orlando International to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

      Knoxville

      18km from central Knoxville
      ClosestCheapest
      from $446
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      Melbourne to Knoxville: Flight information

      The things to know before you go.
      Cheapest flight found$446
      Cheapest month to flyNovember

      Finding cheap flights from Melbourne Orlando International to Knoxville: Frequently asked questions

      The best price we found for a return flight from Melbourne Orlando International to Knoxville is $446. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      Currently, there are no airlines that fly direct from Melbourne Orlando International to Knoxville. But we found flights with one or more stops from $446.
      As of September 2026, there are no flights flying from Melbourne Orlando International to Knoxville.
      The cheapest month to fly from Melbourne Orlando International to Knoxville is usually November.
      After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Melbourne Orlando International Airport to Knoxville Airport on Monday, 23 November 2026.
      No airlines currently offer direct flights between Melbourne Orlando International Airport and Knoxville Airport. Most routes have one or more stops.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

      We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.

      Currently, Delta offers the cheapest flight tickets to Knoxville.

      Flying from Melbourne Orlando International Airport (MLB) to Knoxville Airport (TYS): what you need to know

      • Arriving two hours before an international flight and one hour ahead of a domestic departure are golden rules for hassle-free flying. Show up at the airport on time to board your MLB to TYS flight.

      • Travelling during a peak time like November? Major public holidays and other popular periods can lead to longer lines and delays at check-in and security. Be extra cautious and get there up to four hours ahead of international flights and two hours before domestic departures.

      • Think about adding a stopover when booking your ticket from Melbourne Orlando International Airport to Knoxville Airport. Simply uncheck 'Direct flights only' to break up your trip, or visit a new city along the way. Check out these options between MLB and TYS:

        • Atlanta Hartsfield-Jackson Airport

        • Charlotte Douglas Airport

        • Minneapolis St Paul Airport

      How to find the cheapest flights from Melbourne Orlando International Airport (MLB) to Knoxville Airport (TYS)

      • $220 is the lowest price for a one-way Melbourne Orlando International Airport to Knoxville Airport flight. A return flight starts at $446. These prices can change depending on demand.

      • To get your hands on cheap tickets from MLB to TYS, book in advance. Airlines usually offer their most competitively priced fares when flights are first made available.

      • Finding cheap flights from Melbourne Orlando International Airport to Knoxville Airport is easier if you're flexible with your dates. Use the 'Whole month' search tool to see the lowest prices across every month and score a great deal.

      • Snapping up cheap flights from MLB to TYS is easy with Price Alerts. All you need to do is create one of these automatic alerts and we'll get in touch as soon as a new discounted fare appears.

      • Tailor your trip using filters. Choose your departure and arrival times, airlines and total journey duration. You can also sort your results by 'Fastest,' 'Cheapest' or 'Best' flights from Melbourne Orlando International Airport to Knoxville Airport.

      Handy information about Melbourne Orlando International Airport (MLB)

      • MLB's address is 1 Air Terminal Parkway, Suite 220.

      • 84% of flights leaving Melbourne Orlando International Airport touch down at their destination as planned. Given its dependable on-time performance, disruptions are unlikely when taking off from MLB.

      • Central Melbourne to Melbourne Orlando International Airport is around 11 kilometres. Depending on traffic, it'll take about 15 minutes to get there if you're ride-sharing, catching a taxi or driving.

      • The journey when using public transport usually takes 40 minutes.

      • Taking an early flight from Melbourne Orlando International Airport to Knoxville Airport? Avoid the stress of rushing to the airport (and sneak in some extra snooze time) by picking one of these hotels near MLB:

      Arriving at Knoxville Airport (TYS)

      • Consider booking a hotel close to TYS if you're taking a late Melbourne Orlando International Airport to Knoxville Airport flight. Select one of these options and make your arrival easier:

      • Explore without limits with a Knoxville Airport rental car. Book your wheels from Budget, Alamo or Avis and venture far and wide through Knoxville and beyond.

      • Booking your vehicle from Knoxville Airport around three weeks ahead increases your chances of getting a good deal.

      When to fly to Knoxville Airport (TYS)

      • October is the busiest month for flights from Melbourne Orlando International Airport to Knoxville Airport. To steer clear of the crowds, go to Knoxville in March.

      • The warmest month in Knoxville is July, with temperatures ranging between 17ºC (63ºF) and 32ºC (90ºF). Lock in your flights from Melbourne Orlando International Airport to Knoxville Airport in this month if this is the kind of weather you like.

      • Search for cheap tickets from MLB to TYS in January if you like cooler conditions. Temperatures are at their lowest then, ranging between -6ºC (21ºF) and 11ºC (52ºF) on average.

      Explore more of the United States

      • Columbus is just one of the many cities in the United States waiting to be explored once you've taken in the sights of Knoxville. Around 451 kilometres away to the north, top sights here include Franklin Park Conservatory and Botanical Gardens, Whetstone Park / Park of Roses and Ohio Theatre.

      • If there's time to check out another great destination in the United States, head for Indianapolis, roughly 467 kilometres north-west of Knoxville. Lucas Oil Stadium, Eiteljorg Museum and The Children's Museum of Indianapolis are among its highlights.

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      Plan the rest of your trip from Melbourne to Knoxville

      Prices shown on this page are estimated lowest prices only. Found in the last 12 days.