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Cheap Flights from Istanbul (IST) to Panama City (PTY)

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      Travellers and cabin class, 1 Adult, Economy
      Copa
      Turkish Airlines

      Compare Istanbul to Panama City Tocumen International flight deals

      Find the cheapest month or even day of the year to fly to Panama City Tocumen International

      Book the best Panama City Tocumen International fare with no extra fees

      Flight deals from Istanbul to Panama City Tocumen International

      Looking for a cheap last-minute deal or the best return flight from Istanbul Airport to Panama City Tocumen International Airport? If you want to travel next month, return fares start from $1,267. Find the lowest prices on one-way and return tickets right here.
      Panama City.$1,226 per passenger.Departing Wed, 12 May, returning Tue, 25 May.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Wed, 12 May, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Tue, 25 May, arriving in Istanbul.Price includes taxes and charges.From $1,226, select.
      Panama City.$1,227 per passenger.Departing Fri, 9 Apr, returning Fri, 23 Apr.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Fri, 9 Apr, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Fri, 23 Apr, arriving in Istanbul.Price includes taxes and charges.From $1,227, select.
      Panama City.$1,227 per passenger.Departing Tue, 13 Apr, returning Wed, 5 May.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Tue, 13 Apr, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Wed, 5 May, arriving in Istanbul.Price includes taxes and charges.From $1,227, select.
      Panama City.$1,228 per passenger.Departing Thu, 11 Feb, returning Fri, 12 Mar.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Thu, 11 Feb, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Fri, 12 Mar, arriving in Istanbul.Price includes taxes and charges.From $1,228, select.
      Panama City.$1,228 per passenger.Departing Fri, 19 Feb, returning Sun, 21 Feb.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Fri, 19 Feb, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Sun, 21 Feb, arriving in Istanbul.Price includes taxes and charges.From $1,228, select.
      Panama City.$1,229 per passenger.Departing Fri, 5 Mar, returning Fri, 12 Mar.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Fri, 5 Mar, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Fri, 12 Mar, arriving in Istanbul.Price includes taxes and charges.From $1,229, select.
      Panama City.$1,229 per passenger.Departing Wed, 2 Jun, returning Sun, 6 Jun.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Wed, 2 Jun, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Sun, 6 Jun, arriving in Istanbul.Price includes taxes and charges.From $1,229, select.
      Panama City.$1,232 per passenger.Departing Wed, 4 Nov, returning Sun, 29 Nov.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Wed, 4 Nov, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Sun, 29 Nov, arriving in Istanbul.Price includes taxes and charges.From $1,232, select.
      Panama City.$1,276 per passenger.Departing Tue, 20 Oct, returning Mon, 26 Oct.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Tue, 20 Oct, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Mon, 26 Oct, arriving in Istanbul.Price includes taxes and charges.From $1,276, select.
      Panama City.$1,285 per passenger.Departing Thu, 21 Jan, returning Thu, 4 Feb.Return flight with KLM and Air France.Outbound indirect flight with KLM, departs from Istanbul on Thu, 21 Jan, arriving in Panama City Tocumen International.Inbound indirect flight with Air France, departs from Panama City Tocumen International on Thu, 4 Feb, arriving in Istanbul.Price includes taxes and charges.From $1,285, select.
      Panama City.$1,306 per passenger.Departing Mon, 21 Sep, returning Mon, 5 Oct.Return flight with KLM and Air France.Outbound indirect flight with KLM, departs from Istanbul on Mon, 21 Sep, arriving in Panama City Tocumen International.Inbound indirect flight with Air France, departs from Panama City Tocumen International on Mon, 5 Oct, arriving in Istanbul.Price includes taxes and charges.From $1,306, select.
      Panama City.$1,310 per passenger.Departing Sun, 22 Nov, returning Tue, 1 Dec.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Sun, 22 Nov, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Tue, 1 Dec, arriving in Istanbul.Price includes taxes and charges.From $1,310, select.
      Panama City.$1,313 per passenger.Departing Mon, 26 Oct, returning Mon, 18 Jan.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Mon, 26 Oct, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Mon, 18 Jan, arriving in Istanbul.Price includes taxes and charges.From $1,313, select.
      Panama City.$1,321 per passenger.Departing Fri, 16 Oct, returning Mon, 2 Nov.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Fri, 16 Oct, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Mon, 2 Nov, arriving in Istanbul.Price includes taxes and charges.From $1,321, select.
      Panama City.$1,343 per passenger.Departing Thu, 21 Jan, returning Sun, 31 Jan.Return flight with Air France and KLM.Outbound indirect flight with Air France, departs from Istanbul on Thu, 21 Jan, arriving in Panama City Tocumen International.Inbound indirect flight with KLM, departs from Panama City Tocumen International on Sun, 31 Jan, arriving in Istanbul.Price includes taxes and charges.From $1,343, select.
      Panama City.$1,381 per passenger.Departing Tue, 22 Sep, returning Wed, 30 Sep.Return flight with KLM and Air France.Outbound indirect flight with KLM, departs from Istanbul on Tue, 22 Sep, arriving in Panama City Tocumen International.Inbound indirect flight with Air France, departs from Panama City Tocumen International on Wed, 30 Sep, arriving in Istanbul.Price includes taxes and charges.From $1,381, select.

      Find the cheapest month to fly from Istanbul to Panama City Tocumen International

      We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Istanbul to Panama City Tocumen International flights are currently cheapest in May.
      Sep
      from $1,381
      Oct
      from $1,276
      Nov
      from $1,232
      Dec
      from $1,567
      Jan
      from $1,343
      Feb
      from $1,228
      Mar
      from $1,229
      Apr
      from $1,227
      May
      from $1,226
      Jun
      from $1,229
      Jul
      from $1,816
      Aug
      from $1,951

      Direct flights from Istanbul to Panama City Tocumen International

      Copa
      Turkish Airlines

      Istanbul to Panama City Tocumen International: Alternative routes

      Compare routes from Istanbul to Panama City below. You may find an airport to fly into that's cheaper, faster, or easier than Panama City Tocumen International.

      Panama City Paitilla

      5km from central Panama City
      Closest
      Search flights

      Balboa

      5km from central Panama City
      from $2,992
      Search flights

      Panama City Tocumen International

      18km from central Panama City
      Cheapest
      from $1,218
      Search flights

      Istanbul to Panama City: Flight information

      The things to know before you go.
      Cheapest flight found$1,226
      Cheapest month to flyMay
      Average flight time13 hrs, 50 mins
      Most popular airlineCopa
      Average flights per week6

      Finding cheap flights from Istanbul to Panama City Tocumen International: Frequently asked questions

      The best price we found for a return flight from Istanbul to Panama City Tocumen International is $1,226. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      13 hours and 50 minutes is the average flight time from Istanbul to Panama City Tocumen International.
      Copa and Turkish Airlines fly direct from Istanbul to Panama City Tocumen International.
      As of September 2026, there are 6 flights per week flying from Istanbul to Panama City Tocumen International.
      The cheapest month to fly from Istanbul to Panama City Tocumen International is usually May.
      After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Istanbul Airport to Panama City Tocumen International Airport on Wednesday, 12 May 2027.
      Yes – the average flight time is 13 hours and 50 minutes.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City Tocumen International but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

      We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.

      Currently, Air Europa and Turkish Airlines offer the cheapest flight tickets to Panama City Tocumen International.

      Travelling from Istanbul Airport (IST) to Panama City Tocumen International Airport (PTY): what you need to know

      • Around 13 hours 50 minutes is how long you'll be travelling on a direct flight from Istanbul Airport to Panama City Tocumen International Airport.

      • Panama City is eight hours behind Istanbul and observes the UTC-5 timezone.

      • Choose from three weekly Istanbul Airport to Panama City Tocumen International Airport flights. The 13:50 departure with Turkish Airlines is the earliest flight you can take. Turkish Airlines operates the latest service of the day at 14:10.

      • Arriving two hours before an international flight and one hour ahead of a domestic departure are travel rules to live by. Get to the airport on time to board your IST to PTY flight.

      • You can expect bigger queues in popular months like August. Arriving up to four hours in advance for international flights and two hours for domestic departures is a wise move.

      • Turkish Airlines is your gateway to exploring Panama City (and maybe even some other exciting corners of Panama!). Check out the direct flights from Istanbul Airport to Panama City Tocumen International Airport offered by this airline.

      • The airline that passengers book most often on this route is Turkish Airlines.

      • We make it easy to book a flight with a stopover. To see your options for tickets from Istanbul Airport to Panama City Tocumen International Airport, uncheck 'Direct flights only.' Then, choose a flight with a stop long enough to explore the city of your choice. Stopovers between IST and PTY include:

        • Paris Charles de Gaulle Airport

        • Bogota Airport

        • Havana Airport

      How to find the cheapest flights from Istanbul Airport (IST) to Panama City Tocumen International Airport (PTY)

      • The lowest price we've found for a one-way Istanbul Airport to Panama City Tocumen International Airport flight is $808. A round-trip ticket is currently $1,218. Depending on the availability and when you book, these fares can change.

      • Book one month before travelling. After crunching the numbers on our calendar, this is how far you should book ahead to secure cheap tickets from IST to PTY.

      • Schedule your trip for June. That's the cheapest month for flights from Istanbul Airport to Panama City Tocumen International Airport. If you're flexible with your travel dates, try out the 'Whole month' tool to find the lowest airfare across each month.

      • You don't need to check every day to find out if fares have gone down when you create a Price Alert. We'll update you the moment the price changes on cheap flights from IST to PTY.

      • Secure the ideal flight for you by using the filters. To see the 'Fastest,' 'Best' or 'Cheapest' flights from Istanbul Airport to Panama City Tocumen International Airport, use the 'Sort by' tool. You can also filter results by airline, arrival and departure times, and journey duration.

      Handy information about Istanbul Airport (IST)

      Arriving at Panama City Tocumen International Airport (PTY)

      Getting from Panama City Tocumen International Airport (PTY) to central Panama City

      • Panama City Tocumen International Airport to the centre of Panama City has a drive time of around 35 minutes. It's approximately 24 kilometres away.

      • When travelling on public transport, expect a journey of around 50 minutes.

      When to fly to Panama City Tocumen International Airport (PTY)

      • July is the most popular month for flights from Istanbul Airport to Panama City Tocumen International Airport. To skip the crowds, go to Panama City in March.

      • Before locking in your flight from Istanbul Airport to Panama City Tocumen International Airport, consider the type of weather you like. March is the warmest month in Panama City, with the temperature ranging from 21ºC (70ºF) to 32ºC (90ºF).

      • January sees average temperatures of between 22ºC (72ºF) and 31ºC (88ºF). Look for cheap tickets from IST to PTY sometime then if you want to travel when it's cooler.

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      Prices shown on this page are estimated lowest prices only. Found in the last 12 days.