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Cheap Flights from Denver (DEN) to Panama City (PTYA)

Compare Denver International to Panama City flight deals

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Flight deals from Denver International to Panama City

Looking for a cheap last-minute deal or the best return flight from Denver International Airport to Panama City? If you want to travel next month, return fares start from $919. Find the lowest prices on one-way and return tickets right here.
Panama City.$861 per passenger.Departing Wed, 10 Mar, returning Wed, 17 Mar.Return flight with Copa.Outbound direct flight with Copa departs from Denver International on Wed, 10 Mar, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Wed, 17 Mar, arriving in Denver International.Price includes taxes and charges.From $861, select.
Panama City.$880 per passenger.Departing Thu, 17 Sep, returning Sun, 20 Sep.Return flight with Copa.Outbound direct flight with Copa departs from Denver International on Thu, 17 Sep, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sun, 20 Sep, arriving in Denver International.Price includes taxes and charges.From $880, select.
Panama City.$882 per passenger.Departing Mon, 9 Nov, returning Sat, 14 Nov.Return flight with Copa.Outbound direct flight with Copa departs from Denver International on Mon, 9 Nov, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sat, 14 Nov, arriving in Denver International.Price includes taxes and charges.From $882, select.
Panama City.$883 per passenger.Departing Fri, 2 Oct, returning Sat, 10 Oct.Return flight with Delta.Outbound indirect flight with Delta, departs from Denver International on Fri, 2 Oct, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departs from Panama City Tocumen International on Sat, 10 Oct, arriving in Denver International.Price includes taxes and charges.From $883, select.
Panama City.$887 per passenger.Departing Sun, 18 Oct, returning Mon, 2 Nov.Return flight with Copa.Outbound direct flight with Copa departs from Denver International on Sun, 18 Oct, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Mon, 2 Nov, arriving in Denver International.Price includes taxes and charges.From $887, select.
Panama City.$887 per passenger.Departing Wed, 27 Jan, returning Mon, 1 Feb.Return flight with Copa.Outbound direct flight with Copa departs from Denver International on Wed, 27 Jan, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Mon, 1 Feb, arriving in Denver International.Price includes taxes and charges.From $887, select.
Panama City.$888 per passenger.Departing Mon, 18 Jan, returning Sun, 24 Jan.Return flight with Copa.Outbound direct flight with Copa departs from Denver International on Mon, 18 Jan, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sun, 24 Jan, arriving in Denver International.Price includes taxes and charges.From $888, select.
Panama City.$897 per passenger.Departing Sat, 1 Aug, returning Fri, 7 Aug.Return flight with Copa.Outbound direct flight with Copa departs from Denver International on Sat, 1 Aug, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Fri, 7 Aug, arriving in Denver International.Price includes taxes and charges.From $897, select.
Panama City.$897 per passenger.Departing Sat, 1 Aug, returning Fri, 7 Aug.Return flight with Delta.Outbound indirect flight with Delta, departs from Denver International on Sat, 1 Aug, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departs from Panama City Tocumen International on Fri, 7 Aug, arriving in Denver International.Price includes taxes and charges.From $897, select.
Panama City.$905 per passenger.Departing Wed, 22 Jul, returning Wed, 19 Aug.Return flight with Copa.Outbound direct flight with Copa departs from Denver International on Wed, 22 Jul, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Wed, 19 Aug, arriving in Denver International.Price includes taxes and charges.From $905, select.
Panama City.$909 per passenger.Departing Sat, 5 Dec, returning Wed, 9 Dec.Return flight with Copa.Outbound direct flight with Copa departs from Denver International on Sat, 5 Dec, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Wed, 9 Dec, arriving in Denver International.Price includes taxes and charges.From $909, select.
Panama City.$910 per passenger.Departing Wed, 22 Jul, returning Fri, 31 Jul.Return flight with United.Outbound indirect flight with United, departs from Denver International on Wed, 22 Jul, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Fri, 31 Jul, arriving in Denver International.Price includes taxes and charges.From $910, select.
Panama City.$911 per passenger.Departing Fri, 16 Oct, returning Thu, 22 Oct.Return flight with Copa.Outbound direct flight with Copa departs from Denver International on Fri, 16 Oct, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Thu, 22 Oct, arriving in Denver International.Price includes taxes and charges.From $911, select.
Panama City.$911 per passenger.Departing Sat, 19 Sep, returning Sat, 3 Oct.Return flight with United.Outbound indirect flight with United, departs from Denver International on Sat, 19 Sep, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Sat, 3 Oct, arriving in Denver International.Price includes taxes and charges.From $911, select.
Panama City.$919 per passenger.Departing Fri, 12 Jun, returning Mon, 15 Jun.Return flight with Copa.Outbound direct flight with Copa departs from Denver International on Fri, 12 Jun, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Mon, 15 Jun, arriving in Denver International.Price includes taxes and charges.From $919, select.
Panama City.$933 per passenger.Departing Wed, 1 Jul, returning Fri, 10 Jul.Return flight with Copa.Outbound direct flight with Copa departs from Denver International on Wed, 1 Jul, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Fri, 10 Jul, arriving in Denver International.Price includes taxes and charges.From $933, select.

Find the cheapest month to fly from Denver International to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Denver International to Panama City flights are currently cheapest in March.
May
Find prices
Jun
from $919
Jul
from $910
Aug
from $897
Sep
from $880
Oct
from $883
Nov
from $882
Dec
from $909
Jan
from $888
Feb
from $1,146
Mar
from $861
Apr
Find prices

Direct flights from Denver International to Panama City

Alternative Denver International to Panama City routes

Looking for the cheapest, fastest or easiest route from Denver International to Panama City? You could fly into the following airports instead.

Panama City Paitilla

5km from central Panama City
Closest
Search flights

Balboa

5km from central Panama City
Search flights

Panama City Tocumen International

18km from central Panama City
Cheapest
from $861
Search flights

Denver to Panama City: Flight information

The things to know before you go.
Cheapest flight found$861
Cheapest month to flyMarch
Average flight time5 hrs, 51 mins
Most popular airlineCopa
Average flights per week19

Finding cheap flights from Denver International to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a return flight from Denver International to Panama City is $861. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
5 hours and 51 minutes is the average flight time from Denver International to Panama City.
Copa and United fly direct from Denver International to Panama City.
As of May 2026, there are 19 flights per week flying from Denver International to Panama City.
The cheapest month to fly from Denver International to Panama City is usually March.
If you're flying from Denver International Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from $861.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Denver International Airport to Panama City on Wednesday, 10 March 2027.
Yes – the average flight time is 5 hours and 51 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In May, the average temperature is usually around 28°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
Currently, Copa offers the cheapest flight tickets to Panama City.

Flying from Denver International Airport (DEN) to Panama City: what you need to know

  • Expect to be in the air for 6 hours 20 minutes. On average, that's the time it takes for a direct flight from Denver International Airport to Panama City.

  • Panama City is two hours ahead of Denver, where Denver International Airport is located. Panama City runs on the UTC-5 timezone.

  • Denver International Airport (DEN) to Panama City Tocumen International Airport (PTY) is the most traveled route, with six flights a week to pick from. You can travel from DEN to PTY at 20:19 with Copa Airlines.

  • For a smooth journey, arrive at the airport two hours ahead of international flights and an hour before domestic departures. That way, you can comfortably catch your DEN to Panama City flight.

  • Travelling during a peak time like July? Major public holidays and other popular seasons can lead to longer lines at security. Play things extra safe and get there up to four hours ahead of international flights and two hours before domestic departures.

  • Begin your journey at DEN and travel nonstop to Panama City Tocumen International Airport (PTY). That's where you can expect to land when searching for Denver International Airport to Panama City tickets.

  • Copa Airlines is a well-known carrier that operates direct flights from Denver International Airport to Panama City.

  • A stopover is the ideal opportunity to break up your trip and possibly even tick off a new city. When browsing for plane tickets from DEN to Panama City, deselect the 'Direct flights only' box to see where you can visit along the way. Some popular options include:

    • Houston George Bush Intercontinental Airport (IAH)

    • Orlando International Airport (MCO)

    • Cancun International Airport (CUN)

  • Located around 31 kilometres from central Denver, DEN can be reached in about 35 minutes by car, depending on traffic. Travelling on public transport will take roughly 35 minutes.

  • Staying the night at a hotel can take the hassle out of reaching the airport on time. If you're looking for a place to stay before your flight from Denver International Airport to Panama City, consider The Westin Denver International Airport. It's a short ride from DEN.

  • Denver International Airport gets high marks for its on-time performance. 80% of flights that take off from DEN reach their destination without delay.

  • DEN is located at 8500 Pena Boulevard.

How to find the cheapest flights from Denver International Airport (DEN) to Panama City

  • $719 is the cheapest price we've found for a one-way Denver International Airport to Panama City flight. A round-trip plane ticket right now is $861. Depending on how early you book and the availability, these fares could change.

  • Booking in advance is often the key to finding a cheap flight from DEN to Panama City. Prices tend to rise as demand increases, so the nearer your departure date, the more expensive your ticket may be.

  • If you can be flexible with your trip dates, check out the 'Whole month' tool. It'll find the lowest price across every month when searching for your Denver International Airport to Panama City ticket.

  • There's no need to check in daily to see if fares have dropped when you set up a Price Alert. We'll update you the moment there's an even bigger deal on cheap flights from DEN to Panama City.

  • Snag an affordable flight from Denver International Airport to Panama City with the help of our filters. Choose your ideal times, number of stops and airlines, then sort the results by 'Cheapest' for the best deals.

Airports in Panama City

Panama City Tocumen International Airport (PTY)

  • Panama City Tocumen International Airport (PTY) to the centre of Panama City takes about 35 minutes by car. The centre is roughly 24 kilometres away.

  • If you're travelling on public transport, expect a journey time of around 50 minutes.

  • If you're arriving on a late flight from Denver International Airport to Panama City, nothing beats the convenience of staying close to the terminal. Pick up your bags from the carousel and then be showered and sleeping soon after at one of these accommodation options near PTY:

  • To get the lowest price, book your ride from Panama City Tocumen International Airport around three weeks ahead of your flight from DEN to Panama City.

Panama Pacifico International Airport (BLB)

  • Panama Pacifico International Airport (BLB) is roughly 6 kilometres from the centre of Panama City. Following your flight from Denver International Airport to Panama City, it'll take you around 10 minutes to get to the heart of the city in a ride-share or taxi.

  • If you're catching public transport, it'll take about 20 minutes.

  • Place the 'Do not disturb' sign on your door and rest at a hotel close to BLB. Here are a few options where you can settle in after your DEN to Panama City flight:

  • Get the lowest price by booking your ride from BLB one week in advance. You'll also have access to a wider selection of vehicles.

Best time to go to Panama City

  • It's time to plan your trip dates for your flight from Denver International Airport to Panama City. January is the most popular month to travel to Panama City. If you want a more relaxed atmosphere, go in September.

  • Before locking in your Denver International Airport to Panama City plane ticket, think about what kind of weather you prefer. March is the warmest month in Panama City, with temperatures ranging from 21ºC (70ºF) to 32ºC (90ºF).

  • If you want to travel in cooler conditions, search for a cheap ticket from DEN to Panama City in January when temperatures average between 22ºC (72ºF) and 31ºC (88ºF).

More about Panama City

  • After booking your flight from Denver International Airport to Panama City, choose a hotel that combines comfort with a great location. Make one of these options your base for exploring Panama City:

  • Every great holiday has to include a little sightseeing. Metropolitan Cathedral (Catedral Metropolitan), Casco Viejo and Independence Square are essential stops on your Panama City itinerary.

Explore more of Panama

  • David is just one of the many places in Panama waiting to be explored once you've seen the sights of Panama City. Around 322 kilometres away to the west, its best attractions include Museo Antropológico y Etnográfico Dr. Roberto De La Guardia, Raptors To The Rescue and Unachi Botanical garden.

  • Have time for another stop? Make your way to Santiago de Veraguas. It's located about 193 kilometres southwest of Panama City and home to highlights like Santiago the Apostle Cathedral, Santiago de Veraguas.

Plan the rest of your trip from Denver to Panama City

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.