Cheap Flights from Brussels (BRU) to Panama City (PTYA)

Compare Brussels International to Panama City flight deals

Find the cheapest month or even day of the year to fly to Panama City

Book the best Panama City fare with no extra fees

Flight deals from Brussels International to Panama City

Looking for a cheap last-minute deal or the best return flight from Brussels International to Panama City? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Brussels International to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Brussels International to Panama City flights are currently cheapest in April.

Alternative Brussels International to Panama City routes

Looking for the cheapest, fastest or easiest route from Brussels International to Panama City? You could fly into the following airports instead.

Brussels to Panama City: Flight information

The things to know before you go.
Cheapest flight found$944
Cheapest month to flyApril

Finding cheap flights from Brussels International to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a return flight from Brussels International to Panama City is $944. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Brussels International to Panama City. But we found flights with one or more stops from $944.
As of September 2025, there are no flights flying from Brussels International to Panama City.
The cheapest month to fly from Brussels International to Panama City is usually April.
If you're flying from Brussels International Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from $944.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Brussels International Airport to Panama City on Wednesday, 1 April 2026.
No airlines currently offer direct flights between Brussels International Airport and Panama City. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In September, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
Currently, United offers the cheapest flight tickets to Panama City.

Flying from Brussels Airport (BRU) to Panama City: what you need to know

  • Brussels Airport is located in Brussels. Based in the UTC-5 timezone, Panama City is six hours behind Brussels.

  • To avoid missing your BRU to Panama City flight, allow plenty of time to check in and find your gate. Arriving two hours ahead of international departures and an hour before domestic flights is the general rule.

  • Travelling during a peak time like public or school holidays? Expect longer queues at security and check-in. Give yourself extra leeway and arrive up to four hours before international flights and two hours before domestic departures.

  • A stopover is the ideal opportunity to take a break from travelling and maybe even explore a different city. When browsing for flight tickets from BRU to Panama City, deselect the 'Direct flights only' box to see where you can stop along the way. Here are some options to consider:

    • Amsterdam Airport Schiphol (AMS)

    • Adolfo Suarez Madrid-Barajas Airport (MAD)

    • Newark Liberty International Airport (EWR)

  • Located around 8 kilometres from the centre of Brussels, BRU can be reached in about 20 minutes by car (depending on traffic). Travelling on public transport will take roughly 40 minutes.

  • Looking for a hotel close to BRU? If you're catching an early flight from Brussels Airport to Panama City, these accommodation options put the terminal practically at your doorstep:

  • Of the flights that depart from Brussels Airport, 71.97% arrive as scheduled at their destination.

How to find the cheapest flights from Brussels Airport (BRU) to Panama City

  • $552 is the lowest price we've seen for a one-way Brussels Airport to Panama City flight. A round-trip flight ticket right now is $944. Depending on the availability and when you book, these fares could change.

  • Don't wait until the last moment. You're more likely to land cheap flights from BRU to Panama City if you book in advance. Airlines often offer some great early bird discounts.

  • The 'Whole month' search tool will show you the cheapest tickets from Brussels Airport to Panama City throughout the month. It's a great way to snap up a bargain if your trip dates are flexible.

  • Locking in a cheap flight from BRU to Panama City is a breeze with Price Alerts. All you need to do is set up one of these automatic notifications and we'll notify you when a better deal is available.

  • Pick your preferred departure and arrival times, airlines and number of stops with our filters. Then, sort the results for your flight from Brussels Airport to Panama City by 'Fastest,' 'Best' or 'Cheapest.'

Airports in Panama City

Tocumen International Airport (PTY)

  • The distance from Tocumen International Airport (PTY) to central Panama City is roughly 21 kilometres. It'll take you about 20 minutes to reach the centre driving.

  • When travelling by public transport, expect a journey time of about 1 hour 5 minutes.

  • Consider staying in a hotel close to PTY if you're coming in on a late flight from Brussels Airport to Panama City. Select one of these accommodation options and make arrival day easier:

  • Begin your adventure by picking up a Tocumen International Airport rental car. Grab your wheels from Avis, Dollar or MEX and experience the lesser-explored corners of Panama City and beyond.

  • Get the best deal by booking your vehicle from Tocumen International Airport around three weeks before your flight from BRU to Panama City.

Marcos A. Gelabert International Airport (PAC)

  • Marcos A. Gelabert International Airport (PAC) is about 2 kilometres from central Panama City. Once you've hopped off your flight from Brussels Airport to Panama City, it'll take you around 5 minutes to get to the heart of the city in a ride-share or cab.

  • If you choose to travel on public transport, you'll get to the city centre in 25 minutes or so.

  • Following your BRU to Panama City flight, tuck yourself in at a hotel near PAC. These are some comfortable options that'll help you sink into relaxation mode:

  • No time to waste? The fastest way to get to where you're going is with a Marcos A. Gelabert International Airport rental car. Collect a set of wheels from Thrifty, Avis or Alamo and hit the road in a heartbeat.

  • Get the lowest price by booking your ride from PAC three weeks in advance. You can also expect to have a wider selection of vehicles.

Panama Pacifico Airport (BLB)

  • Panama Pacifico Airport (BLB) is around 16 kilometres from central Panama City. It'll take you about 20 minutes to get to the city centre in a ride-share or cab once you've stepped off your flight from Brussels Airport to Panama City.

  • Check in to a hotel close to BLB and go from landing to lounging in your room in a flash. Whether you're arriving on a late BRU to Panama City flight or just want an easier arrival, these accommodation options offer a quick route to a good night's sleep:

  • Whether you're searching for a zippy compact for a solo escape or a full-size SUV to fit the family, you'll find the ideal Panama Pacifico Airport rental car for you. Explore the types of wheels available here from names such as Sixt, Dollar and Thrifty.

  • Enjoy a payoff when you plan ahead. Book your vehicle from BLB one week before your flight from Brussels Airport to Panama City to access the best deals.

Best time to go to Panama City

  • Carefully consider your dates before booking your flight from Brussels Airport to Panama City. The city comes alive in high season, but prices are typically higher and top attractions can be crowded. Plan your trip to Panama City in low season for a more relaxed vibe.

  • Book a Brussels Airport to Panama City flight ticket with a departure in March if you're eager to visit the city during its warmest month. You can expect temperatures to range from 21ºC (70ºF) to 32ºC (90ºF).

  • February sees average temperatures of between 22ºC (72ºF) and 31ºC (88ºF). Look for a cheap ticket from BRU to Panama City around that time if you want to travel when it's cooler.

More about Panama City

  • Start your Panama City trip right by choosing the ideal place to stay. After booking your flight from Brussels Airport to Panama City, browse our selection of hotels including:

  • Every great adventure has to include some sightseeing. Casco Viejo, Panama Canal Museum and Cinta Costera are must-do's during your Panama City adventure.

Explore more of Panama

  • You've done Panama City, now it's time to explore other parts of Panama. Journey about 322 kilometres west to David to check off its leading attractions. From Parque Cervantes to Altos del Rio Park and Coquito Hills Park, you'll have a packed itinerary ahead.

  • If you're interested in discovering another major destination in Panama, head for Santiago de Veraguas, roughly 193 kilometres south-west of Panama City. Santiago the Apostle Cathedral, Santiago de Veraguas, The Church of Jesus Christ of Latter Day Saints and La Placita San Juan De Dios are among its highlights.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.