Cheap Flights from Medellin to Arequipa Region from $480 Return

Flight deals from Medellin to Arequipa Region

Looking for cheap tickets from Medellin to Arequipa Region, or a last-minute trip? Find the lowest prices on one-way and return tickets right here.

Arequipa.$263 per passenger.Departing Fri, 30 Jan.One-way flight with JetSmart.Outbound indirect flight with JetSmart, departs from Medellin Jose Maria Cordova on Fri, 30 Jan, arriving in Arequipa.Price includes taxes and charges.From $263, select.

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Flying from Medellin to Arequipa Region

Arm yourself with these facts on the fly.

Cheapest flight found	$263
Cheapest month to fly	January
Cheapest airport to fly from	Medellin Jose Maria Cordova

How to find cheap flights from Medellin to Arequipa Region

We've compared the best online travel agents and flight providers on the internet to find the cheapest plane tickets from Medellin to Arequipa Region. Other savvy travellers recently found return flights from $480 and one-way tickets from $263 one-way. Ready to join them? Here are a few tips to help you do it the smart way.

Fly from Medellin Jose Maria Cordova into Arequipa

At the moment, the lowest priced flight tickets to Arequipa Region are from Medellin Jose Maria Cordova Airport to Arequipa Airport.

Fly in January

We crunched the flight calendar and found the cheapest time to fly from Medellin to Arequipa Region is currently January.

Flex your dates for the best rates

If you’re flexible on your departure dates, you can use Skyscanner's whole month tool to find the cheapest day of the year to fly from Medellin to anywhere you choose in Arequipa Region.

Watch as fares rise and fall

With Price Alerts, we'll let you know when flight prices from Medellin to Arequipa Region go up or down so you can book when the time is just right.

Relax – these are fee-free flight tickets

With us, there are no added fees – the Arequipa Region to Arequipa Region flight price you see when you search with us is what you pay to the provider.

Frequently asked questions

What's the average Medellin to Arequipa Region flight price?

We looked at all of the upcoming return flights from Medellin to Arequipa Region we could find over the next 12 months. It looks like $480 is the best price. This is good, compared to the average Arequipa Region ticket price of $480.

What is the cheapest month to fly from Medellin to Arequipa Region?

The cheapest month to fly from Medellin to Arequipa Region is currently January.

Which upcoming date is cheapest to fly from Medellin to Arequipa Region on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Medellin to Arequipa Region on Sunday, 18 January 2026.

Are there any direct flights from Medellin to Arequipa Region?

Currently, there aren't any direct flights from Medellin to Arequipa Region, but you can still fly with a stopover.

If I'm flying from Medellin, where in Arequipa Region is cheapest to fly into?

If you're flying from Medellin, the cheapest city in Arequipa Region to fly into is Arequipa. The cheapest airport serving Arequipa at the moment is Arequipa.