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Cheap Flights from Knoxville (TYS) to Syracuse (SYR)

Compare Knoxville to Syracuse flight deals

Find the cheapest month or even day of the year to fly to Syracuse

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Flight deals from Knoxville to Syracuse

Looking for a cheap last-minute deal or the best return flight from Knoxville Airport to Syracuse Airport? If you want to travel next month, return fares start from $439. Find the lowest prices on one-way and return tickets right here.
Syracuse.$394 per passenger.Departing Tue, 24 Nov, returning Tue, 1 Dec.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Tue, 24 Nov, arriving in Syracuse.Inbound indirect flight with Delta, departs from Syracuse on Tue, 1 Dec, arriving in Knoxville.Price includes taxes and charges.From $394, select.
Syracuse.$394 per passenger.Departing Tue, 1 Sep, returning Tue, 8 Sep.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Tue, 1 Sep, arriving in Syracuse.Inbound indirect flight with Delta, departs from Syracuse on Tue, 8 Sep, arriving in Knoxville.Price includes taxes and charges.From $394, select.
Syracuse.$432 per passenger.Departing Fri, 9 Oct, returning Wed, 14 Oct.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Fri, 9 Oct, arriving in Syracuse.Inbound indirect flight with Delta, departs from Syracuse on Wed, 14 Oct, arriving in Knoxville.Price includes taxes and charges.From $432, select.
Syracuse.$432 per passenger.Departing Tue, 1 Dec, returning Mon, 4 Jan.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Tue, 1 Dec, arriving in Syracuse.Inbound indirect flight with Delta, departs from Syracuse on Mon, 4 Jan, arriving in Knoxville.Price includes taxes and charges.From $432, select.
Syracuse.$439 per passenger.Departing Tue, 18 Aug, returning Mon, 24 Aug.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Tue, 18 Aug, arriving in Syracuse.Inbound indirect flight with Delta, departs from Syracuse on Mon, 24 Aug, arriving in Knoxville.Price includes taxes and charges.From $439, select.
Syracuse.$439 per passenger.Departing Thu, 25 Feb, returning Sun, 28 Feb.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Thu, 25 Feb, arriving in Syracuse.Inbound indirect flight with Delta, departs from Syracuse on Sun, 28 Feb, arriving in Knoxville.Price includes taxes and charges.From $439, select.
Syracuse.$523 per passenger.Departing Tue, 1 Dec, returning Wed, 30 Dec.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Tue, 1 Dec, arriving in Syracuse.Inbound indirect flight with Delta, departs from Syracuse on Wed, 30 Dec, arriving in Knoxville.Price includes taxes and charges.From $523, select.
Syracuse.$587 per passenger.Departing Sat, 25 Jul, returning Sun, 26 Jul.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Sat, 25 Jul, arriving in Syracuse.Inbound indirect flight with Delta, departs from Syracuse on Sun, 26 Jul, arriving in Knoxville.Price includes taxes and charges.From $587, select.
Syracuse.$637 per passenger.Departing Tue, 24 Nov, returning Mon, 30 Nov.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Tue, 24 Nov, arriving in Syracuse.Inbound indirect flight with Delta, departs from Syracuse on Mon, 30 Nov, arriving in Knoxville.Price includes taxes and charges.From $637, select.

Find the cheapest month to fly from Knoxville to Syracuse

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Knoxville to Syracuse flights are currently cheapest in September.
Jul
from $587
Aug
from $439
Sep
from $394
Oct
from $432
Nov
from $637
Dec
from $523
Jan
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Feb
from $439
Mar
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Apr
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May
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Jun
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Knoxville to Syracuse: Alternative routes

Compare routes from Knoxville to Syracuse below. You may find an airport to fly into that's cheaper, faster, or easier than Syracuse.

Syracuse

8km from central Syracuse
ClosestCheapest
from $394
Search flights

Ithaca

67km from central Syracuse
from $553
Search flights

Knoxville to Syracuse: Flight information

The things to know before you go.
Cheapest flight found$394
Cheapest month to flyNovember

Finding cheap flights from Knoxville to Syracuse: Frequently asked questions

The best price we found for a return flight from Knoxville to Syracuse is $394. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Knoxville to Syracuse. But we found flights with one or more stops from $394.
As of July 2026, there are no flights flying from Knoxville to Syracuse.
The cheapest month to fly from Knoxville to Syracuse is usually November.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Knoxville Airport to Syracuse Airport on Tuesday, 24 November 2026.
No airlines currently offer direct flights between Knoxville Airport and Syracuse Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Syracuse but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Syracuse is around 40 days in advance, so don’t leave your flight to the last minute.

Currently, Delta offers the cheapest flight tickets to Syracuse.

Flying from Knoxville Airport (TYS) to Syracuse Airport (SYR): what you need to know

  • Arriving two hours before an international flight and one hour ahead of a domestic departure are travel rules to live by. Make sure you're at the airport on time to catch your TYS to SYR flight.

  • Be prepared for bigger queues during popular months such as October. Arriving up to four hours in advance for international flights and two hours for domestic departures is a good idea.

How to find the cheapest flights from Knoxville Airport (TYS) to Syracuse Airport (SYR)

  • Right now, $357 is the cheapest price we've seen for a one-way Knoxville Airport to Syracuse Airport flight. The best price for a return plane ticket is $394. Remember that fares can change due to availability when booking.

  • To score cheap tickets from TYS to SYR, book ahead. Airlines usually offer lower fares when flights are first released.

  • If you're flexible with your travel plans, try using the 'Whole month' search tool. It'll give you the lowest price across the month when searching for a flight from Knoxville Airport to Syracuse Airport.

  • Save time searching for cheap flights from TYS to SYR by setting up a Price Alert. You'll get an email or notification on the app when a new low fare is offered.

  • Discover the right flight for you with the help of the filters. To see the 'Cheapest,' 'Best' or 'Fastest' flights from Knoxville Airport to Syracuse Airport, use the 'Sort by' tool. You can also filter by airline, arrival and departure times, and number of stops.

Handy information about Knoxville Airport (TYS)

  • TYS is located at 2055 Alcoa Highway.

  • 76% of flights leaving from Knoxville Airport land at their destination on time.

  • Central Knoxville to Knoxville Airport is approximately 24 kilometres. Depending on traffic, it'll take about 25 minutes to get there if you're ride-sharing, catching a taxi or driving.

  • Expect a trip time of around 50 minutes on public transport.

  • Need a convenient hotel close to TYS? If you've booked an early flight from Knoxville Airport to Syracuse Airport, these stays will have you sleeping moments from your departure lounge:

Arriving at Syracuse Airport (SYR)

  • If you're landing on a late Knoxville Airport to Syracuse Airport flight, nothing beats the convenience of staying close to the terminal. Grab your suitcases from the carousel and then be tucked up in bed shortly after at one of these accommodation options near SYR:

  • Pick up a Syracuse Airport rental car and discover Syracuse and beyond with your own wheels. Dollar, Hertz and Budget are top providers to choose from here.

  • Reserving your vehicle from Syracuse Airport around one week ahead can help you secure the lowest rate.

When to fly to Syracuse Airport (SYR)

  • August is the most popular month for flights from Knoxville Airport to Syracuse Airport. To escape the crowds, head to Syracuse in January.

  • Book your flight from Knoxville Airport to Syracuse Airport for July if you want to go to Syracuse during its warmest month. Expect temperatures of between 14ºC (57ºF) and 28ºC (82ºF).

  • If you'd rather travel in cooler conditions, search for a cheap ticket from TYS to SYR in January. Average temperatures are between -12ºC (10ºF) and 3ºC (37ºF) then.

Explore more of the United States

  • New York is just one of the many places in the United States waiting to be discovered once you've seen the sights of Syracuse. Around 322 kilometres away to the south-east, its top attractions include Central Park, Statue of Liberty and Metropolitan Museum of Art.

  • If you're eager to discover another great destination in the United States, consider Philadelphia, roughly 354 kilometres south of Syracuse. Independence Hall, Liberty Bell and Philadelphia Museum of Art are among the biggest draws.

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Plan the rest of your trip from Knoxville to Syracuse

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.