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Cheap Flights from Knoxville (TYS) to Charleston (CHS)

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Compare Knoxville to Charleston flight deals

Find the cheapest month or even day of the year to fly to Charleston

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Flight deals from Knoxville to Charleston

Looking for a cheap last-minute deal or the best return flight from Knoxville to Charleston? Find the lowest prices on one-way and return tickets right here.
Charleston.$547 per passenger.Departing Wed, 15 Oct, returning Sat, 18 Oct.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Wed, 15 Oct, arriving in Charleston.Inbound indirect flight with Delta, departs from Charleston on Sat, 18 Oct, arriving in Knoxville.Price includes taxes and charges.From $547, select.
Charleston.$562 per passenger.Departing Thu, 24 Jul, returning Mon, 28 Jul.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Thu, 24 Jul, arriving in Charleston.Inbound indirect flight with Delta, departs from Charleston on Mon, 28 Jul, arriving in Knoxville.Price includes taxes and charges.From $562, select.
Charleston.$652 per passenger.Departing Wed, 11 Jun, returning Sat, 14 Jun.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Wed, 11 Jun, arriving in Charleston.Inbound indirect flight with Delta, departs from Charleston on Sat, 14 Jun, arriving in Knoxville.Price includes taxes and charges.From $652, select.

Find the cheapest month to fly from Knoxville to Charleston

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Knoxville to Charleston flights are currently cheapest in October.
Jun
from $652
Jul
from $562
Aug
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Sep
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Oct
from $547
Nov
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Dec
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Jan
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Feb
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Mar
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Apr
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May
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Knoxville to Charleston: Alternative routes

Compare routes from Knoxville to Charleston below. You may find an airport to fly into that's cheaper, faster, or easier than Charleston.

Knoxville to Charleston: Flight information

The things to know before you go.
Cheapest flight found$547
Cheapest month to flyOctober

Finding cheap flights from Knoxville to Charleston: Frequently asked questions

The best price we found for a return flight from Knoxville to Charleston is $547. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Knoxville to Charleston. But we found flights with one or more stops from $546.
As of June 2025, there are no flights flying from Knoxville to Charleston.
The cheapest month to fly from Knoxville to Charleston is usually June 2025.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Knoxville Airport to Charleston Airport on Wednesday, 15 October 2025.
No airlines currently offer direct flights between Knoxville Airport and Charleston Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Charleston but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Charleston is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Delta offers the cheapest flight tickets to Charleston.

Travelling from McGhee Tyson Airport (TYS) to Charleston International Airport (CHS): what you need to know

  • Charleston's timezone is UTC-4, which is the same as Knoxville.

  • Get to the airport on time so you don't miss your TYS to CHS flight. Be there at least two hours ahead for international flights and an hour early for domestic departures to prevent a last-minute sprint to your gate.

  • Be prepared for longer lines during popular months like July. Arriving up to four hours ahead of an international flight and two hours for a domestic departure will help ensure a smooth travel experience.

How to find the cheapest flights from McGhee Tyson Airport (TYS) to Charleston International Airport (CHS)

  • At the moment, $347 is the lowest price we've seen for a one-way McGhee Tyson Airport to Charleston International Airport flight. The best price for a return ticket is $546. Keep in mind that fares can change due to demand at the time of booking.

  • To get your hands on cheap tickets from TYS to CHS, book ahead. Airlines generally offer the most competitive fares when flights are first released.

  • Finding cheap flights from McGhee Tyson Airport to Charleston International Airport is more likely if you're flexible with your travel dates. Use the 'Whole month' search tool to see the lowest fares across the month and score a great deal.

  • Picking up cheap flights from TYS to CHS is a piece of cake with Price Alerts. All you need to do is create one of these automatic alerts and we'll let you know when a new discounted fare appears.

  • Tailor your trip with filters. Choose your ideal departure and arrival times, airlines and total journey duration. You can also sort results by 'Fastest,' 'Best' or 'Cheapest' flights from McGhee Tyson Airport to Charleston International Airport.

Handy information about McGhee Tyson Airport (TYS)

  • The address for TYS is 2055 Alcoa Highway.

  • Of all flights leaving McGhee Tyson Airport, 78.98% land on schedule at their destination.

  • McGhee Tyson Airport is around 23 kilometres from central Knoxville. If you're driving, catching a cab or ride-sharing from the centre, it'll take 20 minutes or so to arrive, depending on the traffic.

  • Taking an early flight from McGhee Tyson Airport to Charleston International Airport? Avoid rushing to the terminal (and get some extra shut-eye) by choosing one of these stays near TYS:

Arriving at Charleston International Airport (CHS)

Getting from Charleston International Airport (CHS) to central Charleston

  • Charleston International Airport to central Charleston has a drive time of around 30 minutes. It's approximately 21 kilometres away.

  • It takes roughly 3 hours 35 minutes if you're travelling on public transport.

When to fly to Charleston International Airport (CHS)

  • It's time to work out your travel dates for your flight from McGhee Tyson Airport to Charleston International Airport. July is the busiest month to visit Charleston. If you prefer a quieter vibe, go in April.

  • Lock in your flight from McGhee Tyson Airport to Charleston International Airport for July if you want to visit Charleston during its warmest month. Expect temperatures of between 24ºC (75ºF) and 32ºC (90ºF).

  • Search for cheap tickets from TYS to CHS in January if you want to travel in cooler conditions. Temperatures are at their lowest then, ranging between 4ºC (39ºF) and 17ºC (63ºF) on average.

Explore more of United States

  • You've done Charleston, now it's time to explore other corners of United States. Travel about 322 kilometres south-west to Jacksonville to check off its top attractions. From Jacksonville Zoo and Gardens to The Cummer Museum of Art & Gardens and Friendship Fountain, you'll have a packed itinerary ahead.

  • If you're interested in discovering another well-known destination in United States, consider Charlotte, about 290 kilometres north of Charleston. NASCAR Hall of Fame, Freedom Park and Carolinas Aviation Museum are highlights.

Plan the rest of your trip from Knoxville to Charleston

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.