Skyscanner home

Cheap Flights from Santo Domingo (SDQA) to Medellin (MDEA)

Compare Santo Domingo to Medellin flight deals

Find the cheapest month or even day of the year to fly to Medellin

Book the best Medellin fare with no extra fees

Flight deals from Santo Domingo to Medellin

Looking for a cheap last-minute deal or the best return flight from Santo Domingo to Medellin? If you want to travel next month, return fares start from $291. Find the lowest prices on one-way and return tickets right here.
Medellin.$291 per passenger.Departing Tue, 21 Apr, returning Fri, 24 Apr.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Tue, 21 Apr, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Fri, 24 Apr, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From $291, select.
Medellin.$291 per passenger.Departing Tue, 8 Sep, returning Sat, 12 Sep.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Tue, 8 Sep, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Sat, 12 Sep, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From $291, select.
Medellin.$293 per passenger.Departing Sat, 9 May, returning Wed, 13 May.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Sat, 9 May, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Wed, 13 May, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From $293, select.
Medellin.$293 per passenger.Departing Tue, 19 May, returning Mon, 1 Jun.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Tue, 19 May, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Mon, 1 Jun, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From $293, select.
Medellin.$293 per passenger.Departing Tue, 2 Jun, returning Fri, 12 Jun.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Tue, 2 Jun, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Fri, 12 Jun, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From $293, select.
Medellin.$320 per passenger.Departing Mon, 8 Jun, returning Wed, 1 Jul.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Mon, 8 Jun, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Wed, 1 Jul, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From $320, select.
Medellin.$325 per passenger.Departing Fri, 24 Apr, returning Fri, 1 May.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Fri, 24 Apr, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Fri, 1 May, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From $325, select.
Medellin.$343 per passenger.Departing Sat, 15 Aug, returning Tue, 18 Aug.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Sat, 15 Aug, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Tue, 18 Aug, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From $343, select.
Medellin.$349 per passenger.Departing Thu, 30 Jul, returning Thu, 6 Aug.Return flight with Arajet.Outbound indirect flight with Arajet, departs from Santo Domingo Las Americas on Thu, 30 Jul, arriving in Medellin Jose Maria Cordova.Inbound indirect flight with Arajet, departs from Medellin Jose Maria Cordova on Thu, 6 Aug, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From $349, select.
Medellin.$351 per passenger.Departing Tue, 24 Mar, returning Thu, 9 Apr.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Tue, 24 Mar, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Thu, 9 Apr, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From $351, select.
Medellin.$353 per passenger.Departing Tue, 29 Sep, returning Sat, 3 Oct.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Tue, 29 Sep, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Sat, 3 Oct, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From $353, select.
Medellin.$354 per passenger.Departing Fri, 24 Jul, returning Tue, 28 Jul.Return flight with Arajet.Outbound indirect flight with Arajet, departs from Santo Domingo Las Americas on Fri, 24 Jul, arriving in Medellin Jose Maria Cordova.Inbound indirect flight with Arajet, departs from Medellin Jose Maria Cordova on Tue, 28 Jul, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From $354, select.
Medellin.$355 per passenger.Departing Wed, 22 Jul, returning Wed, 29 Jul.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Wed, 22 Jul, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Wed, 29 Jul, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From $355, select.
Medellin.$388 per passenger.Departing Tue, 28 Jul, returning Sat, 8 Aug.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Tue, 28 Jul, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Sat, 8 Aug, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From $388, select.
Medellin.$394 per passenger.Departing Sun, 4 Oct, returning Thu, 8 Oct.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Sun, 4 Oct, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Thu, 8 Oct, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From $394, select.
Medellin.$406 per passenger.Departing Tue, 24 Mar, returning Tue, 31 Mar.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Tue, 24 Mar, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Tue, 31 Mar, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From $406, select.

Find the cheapest month to fly from Santo Domingo to Medellin

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Santo Domingo to Medellin flights are currently cheapest in April.
Mar
from $406
Apr
from $291
May
from $293
Jun
from $293
Jul
from $354
Aug
from $343
Sep
from $291
Oct
from $394
Nov
from $449
Dec
from $843
Jan
from $441
Feb
Find prices

Direct flights from Santo Domingo to Medellin

Alternative Santo Domingo to Medellin routes

Looking for the cheapest, fastest or easiest route from Santo Domingo to Medellin? You could fly into the following airports instead.

Medellin Enrique Olaya Herrera

3km from central Medellin
Closest
from $798
Search flights

Medellin Jose Maria Cordova

19km from central Medellin
Cheapest
from $291
Search flights

Santo Domingo to Medellin: Flight information

The things to know before you go.
Cheapest flight found$291
Cheapest month to flyApril
Average flight time2 hrs, 32 mins
Most popular airlineArajet
Average flights per week136

Finding cheap flights from Santo Domingo to Medellin: Frequently asked questions

There are 2 airports in Medellin: Medellin Enrique Olaya Herrera and Medellin Jose Maria Cordova.
The best price we found for a return flight from Santo Domingo to Medellin is $291. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
2 hours and 32 minutes is the average flight time from Santo Domingo to Medellin.
Arajet, World Ticket Ltd and Copa Airlines Colombia fly direct from Santo Domingo to Medellin.
As of March 2026, there are 34 flights per week flying from Santo Domingo to Medellin.
The cheapest month to fly from Santo Domingo to Medellin is usually April.
If you're flying from Santo Domingo, the cheapest airport near Medellin is Medellin Jose Maria Cordova – which is 18.9 km away from the centre of Medellin. We've found flights into this airport from $291.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Santo Domingo to Medellin on Tuesday, 21 April 2026.
Yes – the average flight time is 2 hours and 32 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Medellin but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Medellin is around 40 days in advance, so don’t leave your flight to the last minute.
In March, the average temperature is usually around 19°C. May is typically the warmest month in Medellin, when it usually averages around 21°C. You can expect the least rain in January. The coldest month is November, with temperatures averaging 15°C. The rainiest month is May.
The cheapest airline that flies to Medellin is Arajet .

How to find cheap flights to Medellin (MDEA) from Santo Domingo (SDQA) in 2024

Looking for cheap tickets from Santo Domingo to Medellin? Return tickets start from $291 and one-way flights to Medellin from Santo Domingo start from $136


Here are a few tips on how to secure the best flight price and make your journey as smooth as possible.

  • Simply hit 'search'. From British Airways to international carriers like Emirates, we compare all major airlines along with the most popular online travel agents to find the cheapest plane tickets.
  • Compare flight deals to Medellin from Santo Domingo from over 1,000 providers. Then choose the cheapest or fastest plane tickets. Flight tickets to Medellin start from $136 one-way.
  • Flex your dates to find the best SDQA-MDEA ticket prices. If you are flexible when it comes to your travel dates, use Skyscanner's 'Whole month' tool to find the cheapest month, and even day to fly to Medellin from Santo Domingo.
  • Set up a Price Alert. You can easily track the fare of your cheap flights by creating an alert. Whenever prices go down or up, you'll get an email or push notification to help make sure you get the best possible flight deal.
  • Fly without stops. Only interested in direct flights between Santo Domingo and Medellin? Make sure to tick 'Direct flights only' when performing a search. If there are direct flights available on the route, these will appear in the results. Airlines that fly direct include: Arajet
    World Ticket Ltd
    Copa Airlines Colombia
    Wingo
  • Find the cheapest Business class flights from Santo Domingo and Medellin. We scour the internet for the best Business, Premium Economy and First Class flight fares to Medellin, too. Check the difference in price as you search – you might just chance upon a last-minute low fare. Note that not all cabin classes are available for every destination or airline.
  • Include nearby airports in your search. Widen your search for Santo Domingo to Medellin flight deals by selecting the "add nearby airports" option. This will allow you to see flight prices for all the nearest airports at your departure point and your destination and could help you save next time you travel.
  • Search for cheap flights regardless of where you are. To get the best flight booking experience when out and about, download the app and search for plane tickets between Santo Domingo and Medellin whenever you want.

Combine your flight to Medellin from Santo Domingo with hotels and car hire

Once you've secured your cheap flight ticket from Santo Domingo to Medellin, discover the best prices and exclusive rates for hotels in Medellin or nearby. You can also compare hundreds of car hire companies in one go so that you get the best car hire price for your trip.


Plan the rest of your trip from Santo Domingo to Medellin

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.