Cheap Flights from Panama City (PTYA) to Sao Paulo (SAOA)

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Flight deals from Panama City to Sao Paulo

Looking for a cheap last-minute deal or the best return flight from Panama City to Sao Paulo? If you want to travel next month, return fares start from $772. Find the lowest prices on one-way and return tickets right here.

Sao Paulo.$658 per passenger.Departing Sat, 31 Oct, returning Thu, 5 Nov.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Sat, 31 Oct, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Thu, 5 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From $658, select.

Sao Paulo.$667 per passenger.Departing Mon, 2 Nov, returning Sat, 7 Nov.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 2 Nov, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Sat, 7 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From $667, select.

Sao Paulo.$716 per passenger.Departing Fri, 30 Oct, returning Fri, 6 Nov.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Fri, 30 Oct, arriving in Sao Paulo Guarulhos.Inbound direct flight with Copa departs from Sao Paulo Guarulhos on Fri, 6 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From $716, select.

Sao Paulo.$717 per passenger.Departing Sun, 25 Oct, returning Fri, 30 Oct.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Sun, 25 Oct, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Fri, 30 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From $717, select.

Sao Paulo.$745 per passenger.Departing Sat, 7 Nov, returning Sat, 14 Nov.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Sat, 7 Nov, arriving in Sao Paulo Guarulhos.Inbound direct flight with Copa departs from Sao Paulo Guarulhos on Sat, 14 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From $745, select.

Sao Paulo.$772 per passenger.Departing Tue, 15 Sep, returning Thu, 17 Sep.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 15 Sep, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Thu, 17 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $772, select.

Sao Paulo.$775 per passenger.Departing Sat, 12 Dec, returning Fri, 5 Feb.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Sat, 12 Dec, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Fri, 5 Feb, arriving in Panama City Tocumen International.Price includes taxes and charges.From $775, select.

Sao Paulo.$776 per passenger.Departing Thu, 29 Apr, returning Mon, 3 May.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Thu, 29 Apr, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Mon, 3 May, arriving in Panama City Tocumen International.Price includes taxes and charges.From $776, select.

Sao Paulo.$776 per passenger.Departing Fri, 16 Oct, returning Tue, 1 Dec.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Fri, 16 Oct, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Tue, 1 Dec, arriving in Panama City Tocumen International.Price includes taxes and charges.From $776, select.

Sao Paulo.$778 per passenger.Departing Mon, 22 Feb, returning Fri, 26 Feb.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 22 Feb, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Fri, 26 Feb, arriving in Panama City Tocumen International.Price includes taxes and charges.From $778, select.

Sao Paulo.$779 per passenger.Departing Mon, 8 Mar, returning Fri, 12 Mar.Return flight with Avianca and GOL Linhas Aéreas.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 8 Mar, arriving in Sao Paulo Guarulhos.Inbound indirect flight with GOL Linhas Aéreas, departs from Sao Paulo Guarulhos on Fri, 12 Mar, arriving in Panama City Tocumen International.Price includes taxes and charges.From $779, select.

Sao Paulo.$779 per passenger.Departing Wed, 20 Jan, returning Wed, 27 Jan.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Wed, 20 Jan, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Wed, 27 Jan, arriving in Panama City Tocumen International.Price includes taxes and charges.From $779, select.

Sao Paulo.$779 per passenger.Departing Tue, 1 Dec, returning Tue, 8 Dec.Return flight with Avianca and GOL Linhas Aéreas.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 1 Dec, arriving in Sao Paulo Guarulhos.Inbound indirect flight with GOL Linhas Aéreas, departs from Sao Paulo Guarulhos on Tue, 8 Dec, arriving in Panama City Tocumen International.Price includes taxes and charges.From $779, select.

Sao Paulo.$780 per passenger.Departing Mon, 22 Feb, returning Fri, 26 Feb.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Mon, 22 Feb, arriving in Sao Paulo Guarulhos.Inbound direct flight with Copa departs from Sao Paulo Guarulhos on Fri, 26 Feb, arriving in Panama City Tocumen International.Price includes taxes and charges.From $780, select.

Sao Paulo.$780 per passenger.Departing Wed, 14 Oct, returning Fri, 16 Oct.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Wed, 14 Oct, arriving in Sao Paulo Guarulhos.Inbound direct flight with Copa departs from Sao Paulo Guarulhos on Fri, 16 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From $780, select.

Sao Paulo.$780 per passenger.Departing Mon, 3 May, returning Thu, 13 May.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Mon, 3 May, arriving in Sao Paulo Guarulhos.Inbound direct flight with Copa departs from Sao Paulo Guarulhos on Thu, 13 May, arriving in Panama City Tocumen International.Price includes taxes and charges.From $780, select.

Find the cheapest month to fly from Panama City to Sao Paulo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Sao Paulo flights are currently cheapest in November.

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Direct flights from Panama City to Sao Paulo

Alternative Panama City to Sao Paulo routes

Looking for the cheapest, fastest or easiest route from Panama City to Sao Paulo? You could fly into the following airports instead.

Panama City to Sao Paulo: Flight information

The things to know before you go.

Cheapest flight found	$658
Cheapest month to fly	October
Average flight time	6 hrs, 55 mins
Most popular airline	Copa
Average flights per week	208

Finding cheap flights from Panama City to Sao Paulo: Frequently asked questions

How many airports are there in Sao Paulo?

There are 4 airports in Sao Paulo: Sao Paulo Congonhas, Sao Paulo Guarulhos, Sao Paulo Viracopos, and Sao Jose Dos Campos.

How much are return flights from Panama City to Sao Paulo?

The best price we found for a return flight from Panama City to Sao Paulo is $658. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

How long does it take to fly from Panama City to Sao Paulo?

6 hours and 55 minutes is the average flight time from Panama City to Sao Paulo.

Which airlines fly direct from Panama City to Sao Paulo?

Copa, GOL Linhas Aéreas and Emirates fly direct from Panama City to Sao Paulo.

How many flights are there a week from Panama City to Sao Paulo?

As of August 2026, there are 208 flights per week flying from Panama City to Sao Paulo.

When is the cheapest time to fly from Panama City to Sao Paulo?

The cheapest month to fly from Panama City to Sao Paulo is usually October.

Which is the cheapest airport to fly into in Sao Paulo?

If you're flying from Panama City, the cheapest airport near Sao Paulo is Sao Paulo Guarulhos – which is 20.4 km away from the centre of Sao Paulo. We've found flights into this airport from $658.

Which upcoming date is cheapest to fly from Panama City to Sao Paulo on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Sao Paulo on Saturday, 31 October 2026.

Can I get a direct flight from Panama City to Sao Paulo?

Yes – the average flight time is 6 hours and 55 minutes.

How can I get the best flight deal from Panama City to Sao Paulo?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Sao Paulo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Sao Paulo?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Sao Paulo is around 40 days in advance, so don’t leave your flight to the last minute.

What’s the weather like in Sao Paulo?

In August, the average temperature is usually around 18°C. February is typically the warmest month in Sao Paulo, when it usually averages around 27°C. You can expect the least rain in August. The coldest month is July, with temperatures averaging 12°C. The rainiest month is January.

Which is the cheapest airline to fly from Panama City to Sao Paulo with?

The cheapest airline that flies to Sao Paulo is Avianca. And the cheapest airline that flies to Sao Paulo Guarulhos Airport is Copa.

Flying from Panama City to Sao Paulo: what you need to know

There are two main airports to choose from in Panama City. Explore your options departing from Panama City Tocumen International Airport (PTY) or Balboa Airport (BLB) when planning your flight from Panama City to Sao Paulo.
Sao Paulo Guarulhos Airport (GRU) and Sao Paulo Viracopos Airport (VCP) are Sao Paulo's major entry points.
Around 6 hours 55 minutes is how long you can expect to be in the air on a direct Panama City to Sao Paulo flight.
Sao Paulo is two hours ahead of Panama City and is in the UTC-3 timezone.
With 35 weekly flights between the two airports, Panama City Tocumen International Airport (PTY) to Sao Paulo Guarulhos Airport (GRU) is the most popular route. Board the first flight from Panama City to Sao Paulo with Copa Airlines at 11:50. If you prefer to get more out of your day before you fly, the last flight from PTY to GRU is with Copa Airlines at 22:01.
To ensure you get on your Panama City to Sao Paulo flight, allow plenty of time to check in and find your gate. Turning up two hours ahead of international departures and an hour before domestic flights is a good rule of thumb.
You can expect bigger queues during popular months like July. Arriving up to four hours ahead of an international flight and two hours for a domestic departure is a smart move.

How to find the cheapest flights from Panama City to Sao Paulo

To snag cheap Panama City to Sao Paulo flights, reserve your trip nine months before your departure.
Plan your trip for February. That's the best month for scoring great bargains on plane tickets from Panama City to Sao Paulo. If your travel dates are not set in stone, use the 'Whole month' tool to see the lowest price across each month.
There's no need to check every day to see if fares have dropped when you set up a Price Alert. We'll let you know when there's a better deal on cheap flights from Panama City to Sao Paulo.
Save money on your Panama City to Sao Paulo flight with the help of our filters. Choose your preferred duration, departure time and airlines, then sort the results by 'Cheapest' for the best deals.

Flying from Panama City

Panama City Tocumen International Airport (PTY)

You can get a direct flight from Panama City to Sao Paulo taking off from Panama City Tocumen International Airport (PTY). Start your journey at PTY and land at Sao Paulo Guarulhos Airport (GRU).
Secure your Panama City to Sao Paulo plane tickets with Copa Airlines. This carrier is a top pick for direct flights from PTY.
Consider adding a stopover to potentially save on your Panama City to Sao Paulo flight. Simply deselect 'Direct flights only' when searching for departures from Panama City Tocumen International Airport. Break up the journey at one of these popular airports:
- Bogota Airport (BOG)
- Lima Airport (LIM)
- Buenos Aires Ministro Pistarini Airport (EZE)
Travelling from central Panama City to PTY takes around 50 minutes on public transport. If you ride-share, drive or grab a taxi, you'll cover the 18 kilometres in 35 minutes or so, depending on traffic conditions.
Have an early flight from Panama City to Sao Paulo? Avoid rushing to the airport (and enjoy a little extra shut-eye) by choosing one of these hotels close to Panama City Tocumen International Airport:
Panama City Tocumen International Airport earns top marks for on-time performance. 88% of flights that depart PTY arrive at their destination without delay.

Balboa Airport (BLB)

Think about adding a stop at Bogota Airport (BOG). It's a key stopover on a Panama City to Sao Paulo flight out of Balboa Airport. Use a longer layover to explore the city, or take advantage of a quick break to get a snack at the airport.
BLB is around 5 kilometres from central Panama City. It'll take you 10 minutes or so to get to the airport if you're driving from the city centre. Public transport takes roughly 20 minutes.
Want to treat yourself to an extra night away before your flight from Panama City to Sao Paulo? Relax in a hotel near Balboa Airport before your adventure officially begins. These stays are calling your name:
Balboa Airport has a track record for punctuality. 88% of flights out of here meet their scheduled arrival times without fail.

Arriving in Sao Paulo

Sao Paulo Guarulhos Airport (GRU)

Sao Paulo Guarulhos Airport (GRU) to central Sao Paulo takes about 45 minutes by car. The centre is roughly 21 kilometres away.
Getting to the centre on public transport will take you around 1 hour 10 minutes.
If you're coming in on a late flight from Panama City to Sao Paulo, few things beat the convenience of staying close to the terminal. Collect your bags from the carousel and then be showered and relaxing not long after at one of these hotels near GRU:
Hit the road running by picking up a Sao Paulo Guarulhos Airport rental car. Grab a set of wheels from Foco, Localiza or Movida and explore beyond Sao Paulo's usual tourist stops.
Reserving your ride from Sao Paulo Guarulhos Airport around two weeks in advance can help you get the lowest rate.

Sao Paulo Congonhas Airport (CGH)

Once your flight from Panama City to Sao Paulo has arrived, you can reach the city centre in around 25 minutes by car. Central Sao Paulo is approximately 8 kilometres from Sao Paulo Congonhas Airport (CGH).
If you're travelling on public transport, it'll take about 50 minutes.
There are some great places ready to welcome you near CGH. Tuck yourself in after your Panama City to Sao Paulo flight at one of these well-located options:
Forget about public transport timetables or taxi lines. Grab a Sao Paulo Congonhas Airport rental car and let the journey unfold your way. Check out the rates and availability from Foco, Localiza and Movida.
Don't pay more than you need to. Reserving your ride three weeks ahead of your arrival at CGH will help you save.

Sao Paulo Viracopos Airport (VCP)

Step off your flight from Panama City to Sao Paulo and travel to your hotel or start exploring right away. The centre of Sao Paulo is around 80 kilometres from Sao Paulo Viracopos Airport (VCP) and usually takes 1 hour 30 minutes to drive there.
Public transport will get you there in about 2 hours 20 minutes.
Stay in control of the next leg of your journey by picking up a Sao Paulo Viracopos Airport rental car. Foco, Localiza and Movida make getting on the road smooth sailing.
Around four weeks before your flight from Panama City to Sao Paulo is the ideal time to book your vehicle from VCP. You're more likely to land a better deal or even pick up some early bird discounts.

Best time to go to Sao Paulo

March is the quietest month for flights from Panama City to Sao Paulo, while July is the most popular. Find the best time to visit Sao Paulo based on whether you want a lively atmosphere or a more laid-back vibe.
The warmest month in Sao Paulo is February, with temperatures ranging between 18ºC (64ºF) and 29ºC (84ºF). Book your Panama City to Sao Paulo ticket then if that's your idea of comfortable weather.
Search for cheap flights from Panama City to Sao Paulo in July if you like travelling in cooler conditions. Temperatures are at their lowest then, ranging between 12ºC (54ºF) and 25ºC (77ºF) on average.

More about Sao Paulo

Once you've booked your flight from Panama City to Sao Paulo, take your pick from prime hotels that put you close to the action. Make one of these accommodation options your base for exploring Sao Paulo:
Ibirapuera Park and Av. Paulista are a couple of popular attractions to add to your Sao Paulo must-do list. Keep the sightseeing going at Pinacoteca Do Estado De Sao Paulo.

Explore more of Brazil

You've seen Sao Paulo, now it's time to explore other corners of Brazil. Journey about 499 kilometres northeast to Belo Horizonte to check off its popular sights. From Pampulha Modern Ensemble to Casa do Baile and Igreja São Francisco de Assis, you'll have a packed itinerary ahead.
Curitiba is another favourite destination in Brazil and is around 338 kilometres southwest of Sao Paulo. No trip is complete without a visit to Oscar Niemeyer Museum, Eco Park and Botanical Garden of Curitiba.