Cheap Flights from Harrisburg (MDT) to St Louis (STL)

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      Travellers and cabin class, 1 Adult, Economy

      Compare Harrisburg International to St Louis flight deals

      Find the cheapest month or even day of the year to fly to St Louis

      Book the best St Louis fare with no extra fees

      Flight deals from Harrisburg International to St Louis

      Looking for a cheap last-minute deal or the best return flight from Harrisburg International Airport to St Louis Airport? If you want to travel next month, return fares start from $417. Find the lowest prices on one-way and return tickets right here.

      Find the cheapest month to fly from Harrisburg International to St Louis

      We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Harrisburg International to St Louis flights are currently cheapest in October.

      Harrisburg International to St Louis: Alternative routes

      Compare routes from Harrisburg International to St Louis below. You may find an airport to fly into that's cheaper, faster, or easier than St Louis.

      Harrisburg to St Louis: Flight information

      The things to know before you go.
      Cheapest flight found$417
      Cheapest month to flyOctober

      Finding cheap flights from Harrisburg International to St Louis: Frequently asked questions

      The best price we found for a return flight from Harrisburg International to St Louis is $417. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      Currently, there are no airlines that fly direct from Harrisburg International to St Louis. But we found flights with one or more stops from $417.
      As of September 2026, there are no flights flying from Harrisburg International to St Louis.
      The cheapest month to fly from Harrisburg International to St Louis is usually October.
      After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Harrisburg International Airport to St Louis Airport on Saturday, 3 October 2026.
      No airlines currently offer direct flights between Harrisburg International Airport and St Louis Airport. Most routes have one or more stops.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to St Louis but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

      We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to St Louis is around 40 days in advance, so don’t leave your flight to the last minute.

      Currently, Delta offers the cheapest flight tickets to St Louis.

      Flying from Harrisburg International Airport (MDT) to St Louis Airport (STL): what you need to know

      • St Louis is one hour behind Harrisburg and follows the UTC-6 timezone.

      • Arriving two hours before an international flight and one hour ahead of a domestic departure are golden rules for hassle-free flying. Be at the airport with enough time to catch your MDT to STL flight.

      • Flying during a peak month such as July? Major public holidays and other high seasons can lead to longer lines and delays at security. Play things extra safe and arrive up to four hours before international flights and two hours before a domestic departure.

      • We make it a piece of cake to book a flight with a stopover. To see your options for tickets from Harrisburg International Airport to St Louis Airport, deselect 'Direct flights only.' Then, pick a flight offering a stop long enough to tour your chosen city. Worthwhile stopovers between MDT and STL include:

        • Chicago O'Hare International Airport

        • Detroit Wayne County Airport

        • Washington Dulles Airport

      How to find the cheapest flights from Harrisburg International Airport (MDT) to St Louis Airport (STL)

      • Currently, $379 is the lowest price we've seen for a one-way Harrisburg International Airport to St Louis Airport flight. The best price for a return plane ticket is $417. Keep in mind that fares could change due to demand when booking.

      • Don't leave things to the last moment. You're more likely to get cheap tickets from MDT to STL if you book early. Airlines often offer some excellent early bird deals.

      • If you're flexible with your trip dates, use the 'Whole month' tool. It'll show you the cheapest price in each month when looking for your flight from Harrisburg International Airport to St Louis Airport.

      • Never miss a deal on cheap flights from MDT to STL by creating a Price Alert. You'll receive an email or push notification on the app when a new low fare is offered.

      • Pick your preferred departure and arrival times, airlines and number of stops with the filters. Alternatively, sort your results by 'Cheapest' to see the best deals on flights from Harrisburg International Airport to St Louis Airport.

      Handy information about Harrisburg International Airport (MDT)

      • MDT is located at One Terminal Drive.

      • Of the departures from Harrisburg International Airport, 77% touch down on time at their destination.

      • To get to Harrisburg International Airport from central Harrisburg, it'll take about 20 minutes if you're going by car. Of course, this depends on traffic. It's approximately 14 kilometres from the airport to the city centre.

      • Planning to catch public transport? Expect a trip time of around 40 minutes.

      • Looking for a convenient hotel close to MDT? If you're catching an early flight from Harrisburg International Airport to St Louis Airport, these stays will have you sleeping moments from check-in:

      Arriving at St Louis Airport (STL)

      When to fly to St Louis Airport (STL)

      • July is the most popular month for flights from Harrisburg International Airport to St Louis Airport. To skip the crowds, go to St Louis in March.

      • Lock in your flight from Harrisburg International Airport to St Louis Airport for July if you'd like to visit St Louis during its warmest month. Expect temperatures of between 17ºC (63ºF) and 33ºC (91ºF).

      • Look for cheap tickets from MDT to STL in January if you'd rather travel during cooler conditions. Temperatures are at their lowest then, ranging between -7ºC (19ºF) and 8ºC (46ºF) on average.

      Explore more of the United States

      • St Louis has loads to offer, but there are so many other parts of the United States just waiting to be explored. Around 418 kilometres north-east of St Louis, a visit to Chicago will keep your itinerary packed. Start with popular sights like Millennium Park, Art Institute of Chicago and Willis Tower.

      • Around 370 kilometres east of St Louis, Indianapolis is another essential stop in the United States. Start your sightseeing at Lucas Oil Stadium, Eiteljorg Museum and The Children's Museum of Indianapolis.

      Prices shown on this page are estimated lowest prices only. Found in the last 12 days.