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Cheap Flights from Indianapolis (IND) to Knoxville (TYS)

Compare Indianapolis to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

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Flight deals from Indianapolis to Knoxville

Looking for a cheap last-minute deal or the best return flight from Indianapolis Airport to Knoxville Airport? If you want to travel next month, return fares start from $514. Find the lowest prices on one-way and return tickets right here.
Knoxville.$381 per passenger.Departing Tue, 21 Jul, returning Sat, 25 Jul.Return flight with Delta.Outbound indirect flight with Delta, departs from Indianapolis on Tue, 21 Jul, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Sat, 25 Jul, arriving in Indianapolis.Price includes taxes and charges.From $381, select.
Knoxville.$433 per passenger.Departing Thu, 30 Jul, returning Wed, 5 Aug.Return flight with Delta.Outbound indirect flight with Delta, departs from Indianapolis on Thu, 30 Jul, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Wed, 5 Aug, arriving in Indianapolis.Price includes taxes and charges.From $433, select.
Knoxville.$478 per passenger.Departing Fri, 11 Sep, returning Sat, 12 Sep.Return flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Indianapolis on Fri, 11 Sep, arriving in Knoxville.Inbound indirect flight with Southwest Airlines, departs from Knoxville on Sat, 12 Sep, arriving in Indianapolis.Price includes taxes and charges.From $478, select.
Knoxville.$486 per passenger.Departing Fri, 1 Jan, returning Mon, 1 Feb.Return flight with Delta.Outbound indirect flight with Delta, departs from Indianapolis on Fri, 1 Jan, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Mon, 1 Feb, arriving in Indianapolis.Price includes taxes and charges.From $486, select.
Knoxville.$514 per passenger.Departing Sun, 2 Aug, returning Sat, 8 Aug.Return flight with United.Outbound indirect flight with United, departs from Indianapolis on Sun, 2 Aug, arriving in Knoxville.Inbound indirect flight with United, departs from Knoxville on Sat, 8 Aug, arriving in Indianapolis.Price includes taxes and charges.From $514, select.
Knoxville.$623 per passenger.Departing Fri, 2 Oct, returning Sun, 4 Oct.Return flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Indianapolis on Fri, 2 Oct, arriving in Knoxville.Inbound indirect flight with Southwest Airlines, departs from Knoxville on Sun, 4 Oct, arriving in Indianapolis.Price includes taxes and charges.From $623, select.
Knoxville.$681 per passenger.Departing Fri, 18 Dec, returning Mon, 28 Dec.Return flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Indianapolis on Fri, 18 Dec, arriving in Knoxville.Inbound indirect flight with Southwest Airlines, departs from Knoxville on Mon, 28 Dec, arriving in Indianapolis.Price includes taxes and charges.From $681, select.

Find the cheapest month to fly from Indianapolis to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Indianapolis to Knoxville flights are currently cheapest in July.
Jul
from $381
Aug
from $514
Sep
from $478
Oct
from $623
Nov
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Dec
from $680
Jan
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Feb
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Mar
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Apr
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May
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Jun
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Indianapolis to Knoxville: Alternative routes

Compare routes from Indianapolis to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Knoxville

18km from central Knoxville
ClosestCheapest
from $381
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Indianapolis to Knoxville: Flight information

The things to know before you go.
Cheapest flight found$381
Cheapest month to flyJuly

Finding cheap flights from Indianapolis to Knoxville: Frequently asked questions

The best price we found for a return flight from Indianapolis to Knoxville is $381. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Indianapolis to Knoxville. But we found flights with one or more stops from $381.
As of July 2026, there are no flights flying from Indianapolis to Knoxville.
The cheapest month to fly from Indianapolis to Knoxville is usually July.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Indianapolis Airport to Knoxville Airport on Tuesday, 21 July 2026.
No airlines currently offer direct flights between Indianapolis Airport and Knoxville Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.

Currently, Delta offers the cheapest flight tickets to Knoxville.

Travelling from Indianapolis Airport (IND) to Knoxville Airport (TYS): what you need to know

  • To ensure you catch your IND to TYS flight, leave enough time for things like check-in and baggage drop. Arriving two hours ahead of international departures and one hour before domestic flights is the standard rule.

  • You'll likely experience longer queues in popular months such as October. Arriving up to four hours ahead of international flights and two hours for domestic departures will help ensure a smooth travel experience.

  • We make it a piece of cake to book a flight with a stopover. To see all your options for tickets from Indianapolis Airport to Knoxville Airport, uncheck 'Direct flights only.' Then, choose a flight with a stop long enough to explore your chosen city. Top stopovers between IND and TYS include:

    • Atlanta Hartsfield-Jackson Airport

    • Charlotte Douglas Airport

    • Detroit Wayne County Airport

Handy information about Indianapolis Airport (IND)

  • IND is located at 7800 Col. H. Weir Cook Memorial Drive.

  • 78% of flights departing from Indianapolis Airport reach their destination on schedule.

  • Central Indianapolis to Indianapolis Airport is approximately 18 kilometres. Depending on traffic, it'll take you about 20 minutes to get there if you're driving, ride-sharing or catching a taxi.

  • The trip on public transport usually takes 50 minutes.

  • Catching an early flight from Indianapolis Airport to Knoxville Airport? Avoid the hassle of rushing to the airport (and enjoy a little extra shut-eye) by picking one of these stays close to IND:

Arriving at Knoxville Airport (TYS)

  • The last thing you want is a long trip to your hotel if you're arriving on a late Indianapolis Airport to Knoxville Airport flight. Stay at one of these accommodation options near TYS instead:

  • Pick up a Knoxville Airport rental car and explore Knoxville and beyond with your own wheels. Budget, Alamo and Avis are popular outlets you can book with here.

  • Booking your vehicle from Knoxville Airport about three weeks in advance gives you the best shot at securing a great deal.

Getting from Knoxville Airport (TYS) to central Knoxville

  • TYS is located at 2055 Alcoa Highway.

  • Knoxville Airport to the centre of Knoxville has a drive time of about 25 minutes. It's approximately 24 kilometres away.

  • Getting to the centre by public transport takes around 50 minutes.

When to fly to Knoxville Airport (TYS)

  • The quietest month for a flight from Indianapolis Airport to Knoxville Airport is March, while October is the busiest. Choose the best time to go to Knoxville based on whether you prefer a more relaxed vibe or a faster pace.

  • Lock in your flight from Indianapolis Airport to Knoxville Airport for July if you want to visit Knoxville during its warmest month. You can expect temperatures of between 17ºC (63ºF) and 32ºC (90ºF).

  • January has average temperatures of between -6ºC (21ºF) and 11ºC (52ºF). Search for cheap tickets from IND to TYS sometime then if you like cooler conditions.

Explore more of the United States

  • Columbus is just one of the many places in the United States waiting to be explored once you've seen Knoxville. Around 451 kilometres away to the north, popular attractions include Franklin Park Conservatory and Botanical Gardens, Whetstone Park / Park of Roses and Ohio Theatre.

  • Around 467 kilometres north-west of Knoxville, Indianapolis is another favourite stop in the United States. Get a taste of what this destination has to offer at Lucas Oil Stadium, Eiteljorg Museum and The Children's Museum of Indianapolis.

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Prices shown on this page are estimated lowest prices only. Found in the last 12 days.