Cheap Flights from Santa Ana (SNA) to Medellin (MDEA)

Compare Santa Ana John Wayne to Medellin flight deals

Find the cheapest month or even day of the year to fly to Medellin

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Flight deals from Santa Ana John Wayne to Medellin

Looking for a cheap last-minute deal or the best return flight from Santa Ana John Wayne Airport to Medellin? If you want to travel next month, return fares start from $976. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Santa Ana John Wayne to Medellin

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Santa Ana John Wayne to Medellin flights are currently cheapest in September.

Alternative Santa Ana John Wayne to Medellin routes

Looking for the cheapest, fastest or easiest route from Santa Ana John Wayne to Medellin? You could fly into the following airports instead.

Santa Ana to Medellin: Flight information

The things to know before you go.
Cheapest flight found$976
Cheapest month to flySeptember

Finding cheap flights from Santa Ana John Wayne to Medellin: Frequently asked questions

There are 2 airports in Medellin: Medellin Enrique Olaya Herrera and Medellin Jose Maria Cordova.
The best price we found for a return flight from Santa Ana John Wayne to Medellin is $976. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Santa Ana John Wayne to Medellin. But we found flights with one or more stops from $976.
As of August 2026, there are no flights flying from Santa Ana John Wayne to Medellin.
The cheapest month to fly from Santa Ana John Wayne to Medellin is usually September.
If you're flying from Santa Ana John Wayne Airport, the cheapest airport near Medellin is Medellin Jose Maria Cordova – which is 18.9 km away from the centre of Medellin. We've found flights into this airport from $976.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Santa Ana John Wayne Airport to Medellin on Tuesday, 15 September 2026.
No airlines currently offer direct flights between Santa Ana John Wayne Airport and Medellin. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Medellin but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Medellin is around 40 days in advance, so don’t leave your flight to the last minute.

In August, the average temperature is usually around 18°C. May is typically the warmest month in Medellin, when it usually averages around 21°C. You can expect the least rain in January. The coldest month is November, with temperatures averaging 15°C. The rainiest month is May.
Currently, United offers the cheapest flight tickets to Medellin.

Travelling from John Wayne Airport (SNA) to Medellin: what you need to know

  • The timezone in Medellin is UTC-5. The city is three hours ahead of Santa Ana, where John Wayne Airport is located.

  • Give yourself plenty of time to make your SNA to Medellin flight. As a rule of thumb, arrive two hours before international departures and an hour ahead for domestic flights.

  • During popular months such as July, it's wise to get to the airport earlier than usual. Arrive two hours before domestic departures and four hours ahead for an international flight when you fly during high season in general.

  • Whether you want to discover another city along the way or just have a break, we make it easy to book plane tickets from SNA to Medellin with a stopover. To compare your options, uncheck 'Direct flights only.' New York John F. Kennedy International Airport (JFK) is one of your choices.

  • The journey from central Santa Ana to SNA takes around 30 minutes by public transport. If you ride-share, drive or get a taxi, you'll cover the 8 kilometres in 10 minutes or so, depending on traffic.

  • Searching for a hotel close to SNA? If you're catching an early flight from John Wayne Airport to Medellin, these accommodation options put the terminal practically at your doorstep:

  • John Wayne Airport maintains a strong on-time record, making delays less likely. Departures from SNA arrive on schedule 81% of the time.

  • You'll find SNA at 18601 Airport Way.

How to find the cheapest flights from John Wayne Airport (SNA) to Medellin

  • The lowest price we've seen for a one-way John Wayne Airport to Medellin flight is $481. The cheapest price for a return flight is $976. Remember fares can change due to demand at the time of booking.

  • Don't leave everything to the last minute. You're more likely to find cheap flights from SNA to Medellin if you book early. Airlines often have some amazing early bird rates.

  • The 'Whole month' tool will show you the cheapest tickets from John Wayne Airport to Medellin across each month. It's an easy way to find a bargain if your travel dates are flexible.

  • Locking in a cheap flight from SNA to Medellin couldn't be easier with Price Alerts. All you need to do is set up one of these automatic notifications and we'll let you know when a cheaper option becomes available.

  • Find a cheap flight from John Wayne Airport to Medellin with the help of our filters. Choose your preferred duration, number of stops and airlines, then sort the results by 'Cheapest' to see the best deals.

Airports in Medellin

Medellin Jose Maria Cordova Intl Airport (MDE)

  • The distance from Medellin Jose Maria Cordova Intl Airport (MDE) to central Medellin is roughly 32 kilometres. It'll take you about 45 minutes to get to the centre driving.

  • It typically takes 1 hour 15 minutes to get there by public transport.

  • If you're coming in on a late flight from John Wayne Airport to Medellin, nothing beats the convenience of staying near the terminal. Grab your luggage from the carousel and then be showered and relaxing not long after at one of these hotels near MDE:

  • Lock in the best possible rate by reserving your vehicle from Medellin Jose Maria Cordova Intl Airport about one week in advance of your flight from SNA to Medellin.

Medellin Enrique Olaya Herrera Airport (EOH)

  • Medellin Enrique Olaya Herrera Airport (EOH) is about 5 kilometres from central Medellin. Once you've disembarked your flight from John Wayne Airport to Medellin, it'll take you around 15 minutes to reach the heart of the city in a ride-share or taxi.

  • Travelling by public transport will take around 25 minutes.

  • Place the 'Do not disturb' sign on your door and relax at a hotel near EOH. Here are a few options where you can take a load off after your SNA to Medellin flight:

  • Snap up a deal by securing your ride from EOH one week in advance. You can also expect to have a wider selection of vehicles.

Best time to go to Medellin

  • December is the quietest month for flights from John Wayne Airport to Medellin, while January is the busiest. Work out the best time to go to Medellin based on whether you prefer a laid-back vibe or a more bustling atmosphere.

  • Book a John Wayne Airport to Medellin plane ticket with a departure in August if you're eager to explore the city during its warmest month. You can expect temperatures to range from 9ºC (48ºF) to 27ºC (81ºF).

  • Search for cheap tickets from SNA to Medellin in December if you like travelling in cooler conditions. Temperatures are at their lowest then, ranging between 9ºC (48ºF) and 24ºC (75ºF) on average.

More about Medellin

  • Start your Medellin trip off on the right foot by choosing the perfect place to stay. Once you've booked your flight from John Wayne Airport to Medellin, browse our selection of hotels including:

  • All great adventures should include a little sightseeing. Palacio de Bellas Artes, EcoParque Comuna 13 and Museo comuna 13 are must-visits when exploring Medellin.

Explore more of Colombia

  • Bogota is just one of the many cities in Colombia waiting to be explored after you've experienced Medellin. Around 241 kilometres away to the southeast, its top attractions include Teatro Colon Bogota, Park Simón Bolívar Bogotá City and Museum of Contemporary Art of Bogota.

  • Around 322 kilometres south of Medellin, Cali is another favourite stop in Colombia. Start your sightseeing at Cristo Rey, El Retiro Park and Parque Simón Bolívar.

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.