Cheap Flights from Pisa (PSA) to Brussels (BRU)

Compare Pisa International to Brussels International flight deals

Find the cheapest month or even day of the year to fly to Brussels International

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Flight deals from Pisa International to Brussels International

Looking for a cheap last-minute deal or the best return flight from Pisa International Airport to Brussels International Airport? If you want to travel next month, return fares start from $69. Find the lowest prices on one-way and return tickets right here.

Brussels.$69 per passenger.Departing Tue, 22 Sep, returning Sat, 26 Sep.Return flight with Ryanair.Outbound direct flight with Ryanair departs from Pisa International on Tue, 22 Sep, arriving in Brussels International.Inbound direct flight with Ryanair departs from Brussels International on Sat, 26 Sep, arriving in Pisa International.Price includes taxes and charges.From $69, select.

Brussels.$69 per passenger.Departing Tue, 22 Sep, returning Sat, 3 Oct.Return flight with Ryanair.Outbound direct flight with Ryanair departs from Pisa International on Tue, 22 Sep, arriving in Brussels International.Inbound direct flight with Ryanair departs from Brussels International on Sat, 3 Oct, arriving in Pisa International.Price includes taxes and charges.From $69, select.

Brussels.$98 per passenger.Departing Tue, 13 Oct, returning Sat, 17 Oct.Return flight with Ryanair.Outbound direct flight with Ryanair departs from Pisa International on Tue, 13 Oct, arriving in Brussels International.Inbound direct flight with Ryanair departs from Brussels International on Sat, 17 Oct, arriving in Pisa International.Price includes taxes and charges.From $98, select.

Brussels.$136 per passenger.Departing Sat, 29 Aug, returning Tue, 8 Sep.Return flight with Ryanair.Outbound direct flight with Ryanair departs from Pisa International on Sat, 29 Aug, arriving in Brussels International.Inbound direct flight with Ryanair departs from Brussels International on Tue, 8 Sep, arriving in Pisa International.Price includes taxes and charges.From $136, select.

Brussels.$180 per passenger.Departing Tue, 25 Aug, returning Sat, 29 Aug.Return flight with Ryanair.Outbound direct flight with Ryanair departs from Pisa International on Tue, 25 Aug, arriving in Brussels International.Inbound direct flight with Ryanair departs from Brussels International on Sat, 29 Aug, arriving in Pisa International.Price includes taxes and charges.From $180, select.

Brussels.$269 per passenger.Departing Wed, 13 Jan, returning Mon, 18 Jan.Return flight with Ryanair and Vueling Airlines.Outbound indirect flight with Ryanair, departs from Pisa International on Wed, 13 Jan, arriving in Brussels International.Inbound indirect flight with Vueling Airlines, departs from Brussels International on Mon, 18 Jan, arriving in Pisa International.Price includes taxes and charges.From $269, select.

Brussels.$305 per passenger.Departing Wed, 27 Jan, returning Mon, 1 Feb.Return flight with Ryanair and Vueling Airlines.Outbound indirect flight with Ryanair, departs from Pisa International on Wed, 27 Jan, arriving in Brussels International.Inbound indirect flight with Vueling Airlines, departs from Brussels International on Mon, 1 Feb, arriving in Pisa International.Price includes taxes and charges.From $305, select.

Brussels.$305 per passenger.Departing Thu, 5 Nov, returning Mon, 9 Nov.Return flight with Ryanair and LOT.Outbound indirect flight with Ryanair, departs from Pisa International on Thu, 5 Nov, arriving in Brussels International.Inbound indirect flight with LOT, departs from Brussels International on Mon, 9 Nov, arriving in Pisa International.Price includes taxes and charges.From $305, select.

Brussels.$308 per passenger.Departing Thu, 10 Dec, returning Mon, 14 Dec.Return flight with Ryanair and Vueling Airlines.Outbound indirect flight with Ryanair, departs from Pisa International on Thu, 10 Dec, arriving in Brussels International.Inbound indirect flight with Vueling Airlines, departs from Brussels International on Mon, 14 Dec, arriving in Pisa International.Price includes taxes and charges.From $308, select.

Brussels.$318 per passenger.Departing Wed, 17 Feb, returning Mon, 22 Feb.Return flight with Ryanair and LOT.Outbound indirect flight with Ryanair, departs from Pisa International on Wed, 17 Feb, arriving in Brussels International.Inbound indirect flight with LOT, departs from Brussels International on Mon, 22 Feb, arriving in Pisa International.Price includes taxes and charges.From $318, select.

Brussels.$326 per passenger.Departing Fri, 5 Mar, returning Mon, 8 Mar.Return flight with KLM.Outbound indirect flight with KLM, departs from Pisa International on Fri, 5 Mar, arriving in Brussels International.Inbound indirect flight with KLM, departs from Brussels International on Mon, 8 Mar, arriving in Pisa International.Price includes taxes and charges.From $326, select.

Brussels.$329 per passenger.Departing Thu, 1 Apr, returning Sun, 4 Apr.Return flight with Lufthansa.Outbound indirect flight with Lufthansa, departs from Pisa International on Thu, 1 Apr, arriving in Brussels International.Inbound indirect flight with Lufthansa, departs from Brussels International on Sun, 4 Apr, arriving in Pisa International.Price includes taxes and charges.From $329, select.

Brussels.$336 per passenger.Departing Thu, 1 Oct, returning Sun, 1 Nov.Return flight with KLM.Outbound indirect flight with KLM, departs from Pisa International on Thu, 1 Oct, arriving in Brussels International.Inbound indirect flight with KLM, departs from Brussels International on Sun, 1 Nov, arriving in Pisa International.Price includes taxes and charges.From $336, select.

Brussels.$347 per passenger.Departing Fri, 26 Feb, returning Mon, 1 Mar.Return flight with KLM.Outbound indirect flight with KLM, departs from Pisa International on Fri, 26 Feb, arriving in Brussels International.Inbound indirect flight with KLM, departs from Brussels International on Mon, 1 Mar, arriving in Pisa International.Price includes taxes and charges.From $347, select.

Brussels.$352 per passenger.Departing Fri, 30 Apr, returning Sun, 2 May.Return flight with Lufthansa.Outbound indirect flight with Lufthansa, departs from Pisa International on Fri, 30 Apr, arriving in Brussels International.Inbound indirect flight with Lufthansa, departs from Brussels International on Sun, 2 May, arriving in Pisa International.Price includes taxes and charges.From $352, select.

Brussels.$372 per passenger.Departing Wed, 23 Dec, returning Mon, 4 Jan.Return flight with Ryanair and easyJet.Outbound indirect flight with Ryanair, departs from Pisa International on Wed, 23 Dec, arriving in Brussels International.Inbound indirect flight with easyJet, departs from Brussels International on Mon, 4 Jan, arriving in Pisa International.Price includes taxes and charges.From $372, select.

Find the cheapest month to fly from Pisa International to Brussels International

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Pisa International to Brussels International flights are currently cheapest in September.

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Direct flights from Pisa International to Brussels International

Pisa International to Brussels International: Alternative routes

Compare routes from Pisa International to Brussels below. You may find an airport to fly into that's cheaper, faster, or easier than Brussels International.

Pisa to Brussels: Flight information

The things to know before you go.

Cheapest flight found	$69
Cheapest month to fly	September
Average flight time	1 hr, 50 mins
Most popular airline	Malta Air
Average flights per week	4

Finding cheap flights from Pisa International to Brussels International: Frequently asked questions

How much are return flights from Pisa International to Brussels International?

The best price we found for a return flight from Pisa International to Brussels International is $69. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

How long does it take to fly from Pisa International to Brussels International?

1 hour and 50 minutes is the average flight time from Pisa International to Brussels International.

Which airlines fly direct from Pisa International to Brussels International?

Malta Air and Ryanair fly direct from Pisa International to Brussels International.

How many flights are there a week from Pisa International to Brussels International?

As of August 2026, there are 4 flights per week flying from Pisa International to Brussels International.

When is the cheapest time to fly from Pisa International to Brussels International?

The cheapest month to fly from Pisa International to Brussels International is usually September.

Which upcoming date is cheapest to fly from Pisa International Airport to Brussels International Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Pisa International Airport to Brussels International Airport on Tuesday, 22 September 2026.

Can I get a direct flight from Pisa International Airport to Brussels International Airport?

Yes – the average flight time is 1 hour and 50 minutes.

How can I find the best flight deal to Brussels International?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Brussels International but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Brussels?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Brussels is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly from Pisa International Airport to Brussels International with?

Currently, Ryanair offers the cheapest flight tickets to Brussels International.

Travelling from Pisa International Airport (PSA) to Brussels International Airport (BRU): what you need to know

Around 1 hour 50 minutes is how long you can expect to be travelling on a direct flight from Pisa International Airport to Brussels International Airport.
Pisa and Brussels are both in the UTC+1 timezone. That means you won't have to change your watch when you arrive.
Leave enough time to catch your PSA to BRU flight. As a general rule, turn up two hours before international departures and an hour ahead for domestic flights.
Flying during a peak time like July? Public holidays and other high seasons can lead to longer queues and delays at security. Play it safe and arrive up to four hours ahead of an international flight and two hours before a domestic departure.
Flying into Brussels (and then discovering more of Belgium!) is easy with Ryanair. This popular carrier has direct flights from Pisa International Airport to Brussels International Airport.
The airline that tops the list for bookings on this route is Ryanair.
Among carriers operating PSA to BRU flights, Ryanair is the most consistent for on-time landings.
If you want to break up your flight, just uncheck 'Direct flights only' when searching for your ticket from Pisa International Airport to Brussels International Airport. These are the top stopovers between PSA and BRU:
- Frankfurt am Main Airport
- Barcelona Airport
- Manchester Airport

Handy information about Pisa International Airport (PSA)

Of the departures from Pisa International Airport, 75% land on schedule at their destination.
Central Pisa to Pisa International Airport is around 3 kilometres. Depending on traffic, it'll take about 10 minutes to get there if you're catching a taxi, ride-sharing or driving.
Expect a journey time of around 10 minutes on public transport.
Get your break off to a stress-free start by staying near PSA. Whether you're catching an early flight from Pisa International Airport to Brussels International Airport or just don't like being rushed, these hotels are ideal:

Arriving at Brussels International Airport (BRU)

Reserve a hotel near BRU if you're on a late Pisa International Airport to Brussels International Airport flight. Choose one of these options and skip the long transfer:
Get on the fast track to adventure by picking up a Brussels International Airport rental car. Grab your wheels from Keddy By Europcar, Alamo or Europcar and explore beyond Brussels's main sights.
Lock in the lowest price by reserving your ride from Brussels International Airport about three weeks before your travel date.

When to fly to Brussels International Airport (BRU)

September is the busiest month for flights from Pisa International Airport to Brussels International Airport. For smaller crowds, head to Brussels in March.
Before locking in your flight from Pisa International Airport to Brussels International Airport, think about the kind of weather you like. August is the warmest month in Brussels, with temperatures ranging from 12ºC (54ºF) to 27ºC (81ºF).
January has average temperatures of between -2ºC (28ºF) and 8ºC (46ºF). Search for cheap tickets from PSA to BRU sometime around then if you like cooler conditions.

Explore more of Belgium

Brussels has loads to offer, but there are so many other corners of Belgium just waiting to be explored. About 48 kilometres south of Brussels, a trip to Charleroi will keep your itinerary packed. Don't miss top attractions like Musée de la Photographie, BPS22, Musee d'art de la Province de Hainaut and Le Bois du Cazier.
Liege is another favourite destination in Belgium and is around 88 kilometres east of Brussels. No journey is complete without seeing Cathedral de Liege (Liege Cathedral), Parc De La Citadelle and Parc de la Chartreuse.