Cheap Flights from Minneapolis (MSP) to Guayaquil (GYE)

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Travellers and cabin class, 1 Adult, Economy

Compare Minneapolis St Paul to Guayaquil flight deals

Find the cheapest month or even day of the year to fly to Guayaquil

Book the best Guayaquil fare with no extra fees

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Flight deals from Minneapolis St Paul to Guayaquil

Looking for a cheap last-minute deal or the best return flight from Minneapolis St Paul Airport to Guayaquil Airport? If you want to travel next month, return fares start from $1,358. Find the lowest prices on one-way and return tickets right here.

Guayaquil.$1,026 per passenger.Departing Mon, 24 Aug, returning Tue, 8 Sep.Return flight with Frontier Airlines and Avianca.Outbound indirect flight with Frontier Airlines, departs from Minneapolis St Paul on Mon, 24 Aug, arriving in Guayaquil.Inbound indirect flight with Avianca, departs from Guayaquil on Tue, 8 Sep, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,026, select.

Guayaquil.$1,099 per passenger.Departing Thu, 11 Mar, returning Thu, 25 Mar.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Minneapolis St Paul on Thu, 11 Mar, arriving in Guayaquil.Inbound indirect flight with LATAM Airlines, departs from Guayaquil on Thu, 25 Mar, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,099, select.

Guayaquil.$1,127 per passenger.Departing Sat, 1 May, returning Sat, 8 May.Return flight with Delta.Outbound indirect flight with Delta, departs from Minneapolis St Paul on Sat, 1 May, arriving in Guayaquil.Inbound indirect flight with Delta, departs from Guayaquil on Sat, 8 May, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,127, select.

Guayaquil.$1,128 per passenger.Departing Fri, 27 Nov, returning Sun, 6 Dec.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Minneapolis St Paul on Fri, 27 Nov, arriving in Guayaquil.Inbound indirect flight with LATAM Airlines, departs from Guayaquil on Sun, 6 Dec, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,128, select.

Guayaquil.$1,140 per passenger.Departing Tue, 9 Feb, returning Tue, 16 Feb.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Minneapolis St Paul on Tue, 9 Feb, arriving in Guayaquil.Inbound indirect flight with LATAM Airlines, departs from Guayaquil on Tue, 16 Feb, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,140, select.

Guayaquil.$1,156 per passenger.Departing Sun, 1 Nov, returning Thu, 5 Nov.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Minneapolis St Paul on Sun, 1 Nov, arriving in Guayaquil.Inbound indirect flight with LATAM Airlines, departs from Guayaquil on Thu, 5 Nov, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,156, select.

Guayaquil.$1,196 per passenger.Departing Wed, 2 Dec, returning Sun, 20 Dec.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Minneapolis St Paul on Wed, 2 Dec, arriving in Guayaquil.Inbound indirect flight with LATAM Airlines, departs from Guayaquil on Sun, 20 Dec, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,196, select.

Guayaquil.$1,358 per passenger.Departing Wed, 9 Sep, returning Tue, 15 Sep.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Minneapolis St Paul on Wed, 9 Sep, arriving in Guayaquil.Inbound indirect flight with LATAM Airlines, departs from Guayaquil on Tue, 15 Sep, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,358, select.

Guayaquil.$1,393 per passenger.Departing Thu, 24 Sep, returning Thu, 1 Oct.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Minneapolis St Paul on Thu, 24 Sep, arriving in Guayaquil.Inbound indirect flight with LATAM Airlines, departs from Guayaquil on Thu, 1 Oct, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,393, select.

Guayaquil.$1,572 per passenger.Departing Mon, 12 Oct, returning Thu, 15 Oct.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Minneapolis St Paul on Mon, 12 Oct, arriving in Guayaquil.Inbound indirect flight with LATAM Airlines, departs from Guayaquil on Thu, 15 Oct, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,572, select.

Guayaquil.$1,740 per passenger.Departing Tue, 5 Jan, returning Sat, 23 Jan.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Minneapolis St Paul on Tue, 5 Jan, arriving in Guayaquil.Inbound indirect flight with LATAM Airlines, departs from Guayaquil on Sat, 23 Jan, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,740, select.

Guayaquil.$2,003 per passenger.Departing Mon, 28 Dec, returning Thu, 18 Feb.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Minneapolis St Paul on Mon, 28 Dec, arriving in Guayaquil.Inbound indirect flight with LATAM Airlines, departs from Guayaquil on Thu, 18 Feb, arriving in Minneapolis St Paul.Price includes taxes and charges.From $2,003, select.

Guayaquil.$2,945 per passenger.Departing Mon, 28 Dec, returning Sun, 3 Jan.Return flight with Copa.Outbound indirect flight with Copa, departs from Minneapolis St Paul on Mon, 28 Dec, arriving in Guayaquil.Inbound indirect flight with Copa, departs from Guayaquil on Sun, 3 Jan, arriving in Minneapolis St Paul.Price includes taxes and charges.From $2,945, select.

Minneapolis St Paul to Guayaquil: Alternative routes

Compare routes from Minneapolis St Paul to Guayaquil below. You may find an airport to fly into that's cheaper, faster, or easier than Guayaquil.

Guayaquil

4km from central Guayaquil

ClosestCheapest

from $1,026

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Minneapolis to Guayaquil: Flight information

The things to know before you go.

Cheapest flight found	$1,026
Cheapest month to fly	August

Finding cheap flights from Minneapolis St Paul to Guayaquil: Frequently asked questions

How much are return flights from Minneapolis St Paul to Guayaquil?

The best price we found for a return flight from Minneapolis St Paul to Guayaquil is $1,026. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Minneapolis St Paul to Guayaquil?

Currently, there are no airlines that fly direct from Minneapolis St Paul to Guayaquil. But we found flights with one or more stops from $1,026.

How many flights are there a week from Minneapolis St Paul to Guayaquil?

As of August 2026, there are no flights flying from Minneapolis St Paul to Guayaquil.

When is the cheapest time to fly from Minneapolis St Paul to Guayaquil?

The cheapest month to fly from Minneapolis St Paul to Guayaquil is usually August.

Which upcoming date is cheapest to fly from Minneapolis St Paul Airport to Guayaquil Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Minneapolis St Paul Airport to Guayaquil Airport on Monday, 24 August 2026.

Can I get a direct flight from Minneapolis St Paul Airport to Guayaquil Airport?

No airlines currently offer direct flights between Minneapolis St Paul Airport and Guayaquil Airport. Most routes have one or more stops.

How can I find the best flight deal to Guayaquil?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Guayaquil but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Guayaquil?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Guayaquil is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly from Minneapolis St Paul Airport to Guayaquil with?

Currently, Frontier Airlines offers the cheapest flight tickets to Guayaquil.

Flying from Minneapolis St Paul Airport (MSP) to Guayaquil Airport (GYE): what you need to know

Guayaquil's timezone is UTC-5, which makes Guayaquil one hour ahead of Minneapolis.
To ensure you catch your MSP to GYE flight, leave plenty of time to check in and find your gate. Arriving two hours before international departures and one hour before domestic flights is the standard rule.
During popular months such as July, it's best to get to the airport earlier than usual. Plan to arrive two hours before a domestic departure and four hours ahead for an international flight whenever you're travelling during peak periods in general.
If you'd like to explore another city along the way, just deselect 'Direct flights only' when searching for your ticket from Minneapolis St Paul Airport to Guayaquil Airport. Here are the most popular stopovers between MSP and GYE:
- New York John F. Kennedy Airport
- Miami International Airport
- Fort Lauderdale International Airport

Handy information about Minneapolis St Paul Airport (MSP)

You'll find MSP at 6040 28th Avenue South.
77% of flights leaving from Minneapolis St Paul Airport arrive at their destination on schedule.
Central Minneapolis to Minneapolis St Paul Airport is around 18 kilometres. Depending on traffic, it'll take about 20 minutes to get there if you're driving, ride-sharing or catching a taxi.
The journey on public transport will take about 25 minutes.
Have an early flight from Minneapolis St Paul Airport to Guayaquil Airport? Avoid the last-minute rush to the terminal (and sneak in some extra precious sleep) by choosing one of these stays near MSP:

Arriving at Guayaquil Airport (GYE)

If you're getting in on a late Minneapolis St Paul Airport to Guayaquil Airport flight, few things beat the convenience of staying close to the terminal. Pick up your bags from the carousel and then be resting not long after at one of these accommodation options near GYE:
Follow your own route with a Guayaquil Airport rental car. Book your wheels from Europcar, Keddy By Europcar or Goldcar and find adventure across Guayaquil and beyond.
Lock in the best deal by reserving your vehicle from Guayaquil Airport around four weeks ahead of your trip.

When to fly to Guayaquil Airport (GYE)

It's time to choose your travel dates for your flight from Minneapolis St Paul Airport to Guayaquil Airport. July is the most popular month to head to Guayaquil. If you prefer a more laid-back vibe, go in March.
Lock in your flight from Minneapolis St Paul Airport to Guayaquil Airport for November if you'd like to go to Guayaquil during its warmest month. Expect temperatures of between 19ºC (66ºF) and 33ºC (91ºF).
Search for cheap tickets from MSP to GYE in August if you like travelling in cooler conditions. Temperatures are at their lowest around then, ranging between 19ºC (66ºF) and 32ºC (90ºF) on average.

Explore more of Ecuador

Guayaquil has plenty going for it, but there are so many other corners of Ecuador waiting to be discovered. About 274 kilometres north-east of Guayaquil, a trip to Quito will keep your itinerary packed. Start with attractions like Quito Historic Centre, Catedral Metropolitana de Quito and Camino de los Incas.
If you want to check out another great destination in Ecuador, consider Cuenca, about 129 kilometres south-east of Guayaquil. Inca Ruins, New Cathedral (Catedral de la Immaculada) and Old Cathedral of Cuenca are key highlights.