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Cheap Flights from Des Moines (DSM) to Myrtle Beach (MYR)

Compare Des Moines to Myrtle Beach International flight deals

Find the cheapest month or even day of the year to fly to Myrtle Beach International

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Flight deals from Des Moines to Myrtle Beach International

Looking for a cheap last-minute deal or the best return flight from Des Moines Airport to Myrtle Beach International Airport? If you want to travel next month, return fares start from $485. Find the lowest prices on one-way and return tickets right here.
Myrtle Beach.$485 per passenger.Departing Tue, 1 Sep, returning Wed, 9 Sep.Return flight with United.Outbound indirect flight with United, departs from Des Moines on Tue, 1 Sep, arriving in Myrtle Beach International .Inbound indirect flight with United, departs from Myrtle Beach International on Wed, 9 Sep, arriving in Des Moines.Price includes taxes and charges.From $485, select.
Myrtle Beach.$490 per passenger.Departing Sat, 29 Aug, returning Wed, 2 Sep.Return flight with Delta.Outbound indirect flight with Delta, departs from Des Moines on Sat, 29 Aug, arriving in Myrtle Beach International .Inbound indirect flight with Delta, departs from Myrtle Beach International on Wed, 2 Sep, arriving in Des Moines.Price includes taxes and charges.From $490, select.
Myrtle Beach.$491 per passenger.Departing Sat, 26 Sep, returning Sat, 3 Oct.Return flight with United.Outbound indirect flight with United, departs from Des Moines on Sat, 26 Sep, arriving in Myrtle Beach International .Inbound indirect flight with United, departs from Myrtle Beach International on Sat, 3 Oct, arriving in Des Moines.Price includes taxes and charges.From $491, select.
Myrtle Beach.$590 per passenger.Departing Mon, 1 Mar, returning Thu, 8 Apr.Return flight with Delta.Outbound indirect flight with Delta, departs from Des Moines on Mon, 1 Mar, arriving in Myrtle Beach International .Inbound indirect flight with Delta, departs from Myrtle Beach International on Thu, 8 Apr, arriving in Des Moines.Price includes taxes and charges.From $590, select.
Myrtle Beach.$747 per passenger.Departing Thu, 20 Aug, returning Mon, 24 Aug.Return flight with Delta.Outbound indirect flight with Delta, departs from Des Moines on Thu, 20 Aug, arriving in Myrtle Beach International .Inbound indirect flight with Delta, departs from Myrtle Beach International on Mon, 24 Aug, arriving in Des Moines.Price includes taxes and charges.From $747, select.
Myrtle Beach.$805 per passenger.Departing Thu, 15 Apr, returning Sun, 18 Apr.Return flight with Delta.Outbound indirect flight with Delta, departs from Des Moines on Thu, 15 Apr, arriving in Myrtle Beach International .Inbound indirect flight with Delta, departs from Myrtle Beach International on Sun, 18 Apr, arriving in Des Moines.Price includes taxes and charges.From $805, select.
Myrtle Beach.$933 per passenger.Departing Mon, 2 Nov, returning Thu, 5 Nov.Return flight with Delta.Outbound indirect flight with Delta, departs from Des Moines on Mon, 2 Nov, arriving in Myrtle Beach International .Inbound indirect flight with Delta, departs from Myrtle Beach International on Thu, 5 Nov, arriving in Des Moines.Price includes taxes and charges.From $933, select.
Myrtle Beach.$1,124 per passenger.Departing Mon, 15 Mar, returning Fri, 19 Mar.Return flight with Delta.Outbound indirect flight with Delta, departs from Des Moines on Mon, 15 Mar, arriving in Myrtle Beach International .Inbound indirect flight with Delta, departs from Myrtle Beach International on Fri, 19 Mar, arriving in Des Moines.Price includes taxes and charges.From $1,124, select.
Myrtle Beach.$1,373 per passenger.Departing Fri, 9 Oct, returning Sun, 11 Oct.Return flight with United.Outbound indirect flight with United, departs from Des Moines on Fri, 9 Oct, arriving in Myrtle Beach International .Inbound indirect flight with United, departs from Myrtle Beach International on Sun, 11 Oct, arriving in Des Moines.Price includes taxes and charges.From $1,373, select.

Find the cheapest month to fly from Des Moines to Myrtle Beach International

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Des Moines to Myrtle Beach International flights are currently cheapest in September.
Aug
from $747
Sep
from $485
Oct
from $1,373
Nov
from $933
Dec
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Jan
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Feb
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Mar
from $1,124
Apr
from $805
May
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Jun
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Jul
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Des Moines to Myrtle Beach International : Alternative routes

Compare routes from Des Moines to Myrtle Beach below. You may find an airport to fly into that's cheaper, faster, or easier than Myrtle Beach International .

Myrtle Beach International

5km from central Myrtle Beach
ClosestCheapest
from $485
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Des Moines to Myrtle Beach: Flight information

The things to know before you go.
Cheapest flight found$485
Cheapest month to flySeptember

Finding cheap flights from Des Moines to Myrtle Beach International : Frequently asked questions

The best price we found for a return flight from Des Moines to Myrtle Beach International is $485. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Des Moines to Myrtle Beach International . But we found flights with one or more stops from $485.
As of August 2026, there are no flights flying from Des Moines to Myrtle Beach International .
The cheapest month to fly from Des Moines to Myrtle Beach International is usually September.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Des Moines Airport to Myrtle Beach International Airport on Tuesday, 1 September 2026.
No airlines currently offer direct flights between Des Moines Airport and Myrtle Beach International Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Myrtle Beach International but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Myrtle Beach is around 40 days in advance, so don’t leave your flight to the last minute.

Currently, United offers the cheapest flight tickets to Myrtle Beach International .

Flying from Des Moines Airport (DSM) to Myrtle Beach International Airport (MYR): what you need to know

  • To ensure you get on your DSM to MYR flight, leave plenty of time to check in and drop off your luggage. Arriving two hours ahead of international departures and an hour before domestic flights is the general rule.

  • During popular months such as August, you'll want to get to the airport well in advance. Arrive two hours before domestic departures and four hours ahead for an international flight when you fly during a peak period in general.

  • Think about adding a stopover when booking your ticket from Des Moines Airport to Myrtle Beach International Airport. Simply uncheck 'Direct flights only' to break up your journey, or enjoy a detour to a new and interesting place. Check out these options between DSM and MYR:

    • Chicago O'Hare International Airport

    • Charlotte Douglas Airport

    • Detroit Wayne County Airport

Handy information about Des Moines Airport (DSM)

  • DSM's address is 5800 Fleur Drive, Suite 201.

  • Of all flights departing from Des Moines Airport, 77% land on time at their destination.

  • Central Des Moines to Des Moines Airport is around 11 kilometres. Depending on traffic, it'll take about 15 minutes to get there if you're driving, ride-sharing or catching a taxi.

  • You can expect a trip time of roughly 30 minutes when using public transport.

  • Taking an early flight from Des Moines Airport to Myrtle Beach International Airport? Avoid the hassle of rushing to the terminal (and catch some extra z's) by choosing one of these hotels close to DSM:

Arriving at Myrtle Beach International Airport (MYR)

When to fly to Myrtle Beach International Airport (MYR)

  • The quietest month for a flight from Des Moines Airport to Myrtle Beach International Airport is March, while July is the most popular. Pick the best time to visit Myrtle Beach based on whether you prefer a more relaxed vibe or a faster pace.

  • Book your flight from Des Moines Airport to Myrtle Beach International Airport for July if you want to go to Myrtle Beach during its warmest month. You can expect temperatures of between 23ºC (73ºF) and 31ºC (88ºF).

  • Look for cheap tickets from DSM to MYR in January if you like cooler conditions. Temperatures are at their lowest around then, ranging between 2ºC (36ºF) and 16ºC (61ºF) on average.

Explore more of the United States

  • Myrtle Beach has plenty to offer, but there are so many other corners of the United States you'll want to see. Around 451 kilometres south-west of Myrtle Beach, a visit to Jacksonville will keep you busy. Start with leading sights like St. John's Cathedral, Museum of Contemporary Art Jacksonville and The Cummer Museum of Art & Gardens.

  • If you're looking to explore another well-known destination in the United States, head for Charlotte, about 241 kilometres north-west of Myrtle Beach. Bechtler Museum of Modern Art, Discovery Place and NASCAR Hall of Fame are key reasons to visit.

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Plan the rest of your trip from Des Moines to Myrtle Beach

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.