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Cheap Flights from Columbia (CAE) to Knoxville (TYS)

Compare Columbia Metropolitan to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

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Flight deals from Columbia Metropolitan to Knoxville

Looking for a cheap last-minute deal or the best return flight from Columbia Metropolitan Airport to Knoxville Airport? If you want to travel next month, return fares start from $534. Find the lowest prices on one-way and return tickets right here.
Knoxville.$534 per passenger.Departing Thu, 3 Sep, returning Wed, 9 Sep.Return flight with Delta.Outbound indirect flight with Delta, departs from Columbia Metropolitan on Thu, 3 Sep, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Wed, 9 Sep, arriving in Columbia Metropolitan.Price includes taxes and charges.From $534, select.
Knoxville.$570 per passenger.Departing Sat, 29 Aug, returning Fri, 4 Sep.Return flight with Delta.Outbound indirect flight with Delta, departs from Columbia Metropolitan on Sat, 29 Aug, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Fri, 4 Sep, arriving in Columbia Metropolitan.Price includes taxes and charges.From $570, select.
Knoxville.$647 per passenger.Departing Fri, 21 Aug, returning Tue, 25 Aug.Return flight with Delta.Outbound indirect flight with Delta, departs from Columbia Metropolitan on Fri, 21 Aug, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Tue, 25 Aug, arriving in Columbia Metropolitan.Price includes taxes and charges.From $647, select.
Knoxville.$829 per passenger.Departing Mon, 28 Dec, returning Tue, 29 Dec.Return flight with Delta.Outbound indirect flight with Delta, departs from Columbia Metropolitan on Mon, 28 Dec, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Tue, 29 Dec, arriving in Columbia Metropolitan.Price includes taxes and charges.From $829, select.
Knoxville.$1,112 per passenger.Departing Tue, 22 Dec, returning Sat, 2 Jan.Return flight with Delta.Outbound indirect flight with Delta, departs from Columbia Metropolitan on Tue, 22 Dec, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Sat, 2 Jan, arriving in Columbia Metropolitan.Price includes taxes and charges.From $1,112, select.

Find the cheapest month to fly from Columbia Metropolitan to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Columbia Metropolitan to Knoxville flights are currently cheapest in September.
Aug
from $647
Sep
from $534
Oct
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Nov
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Dec
from $829
Jan
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Feb
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Mar
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Apr
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May
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Jun
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Jul
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Columbia Metropolitan to Knoxville: Alternative routes

Compare routes from Columbia Metropolitan to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Knoxville

18km from central Knoxville
ClosestCheapest
from $534
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Columbia to Knoxville: Flight information

The things to know before you go.
Cheapest flight found$534
Cheapest month to flySeptember

Finding cheap flights from Columbia Metropolitan to Knoxville: Frequently asked questions

The best price we found for a return flight from Columbia Metropolitan to Knoxville is $534. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Columbia Metropolitan to Knoxville. But we found flights with one or more stops from $534.
As of August 2026, there are no flights flying from Columbia Metropolitan to Knoxville.
The cheapest month to fly from Columbia Metropolitan to Knoxville is usually September.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Columbia Metropolitan Airport to Knoxville Airport on Thursday, 3 September 2026.
No airlines currently offer direct flights between Columbia Metropolitan Airport and Knoxville Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.

Currently, Delta offers the cheapest flight tickets to Knoxville.

Flying from Columbia Metropolitan Airport (CAE) to Knoxville Airport (TYS): what you need to know

  • For a stress-free journey, arrive at the airport two hours ahead of international flights and one hour before domestic departures. This way, you can comfortably board your CAE to TYS flight.

  • Flying during a peak time such as October? School holidays and other high seasons can mean longer queues and delays at check-in and security. Be extra cautious and get there up to four hours before international flights and two hours before a domestic departure.

  • If you'd like to add a stop to your trip, simply deselect 'Direct flights only' when searching for your ticket from Columbia Metropolitan Airport to Knoxville Airport. Here are the top stopovers between CAE and TYS:

    • Atlanta Hartsfield-Jackson Airport

    • Charlotte Douglas Airport

    • Washington Dulles Airport

How to find the cheapest flights from Columbia Metropolitan Airport (CAE) to Knoxville Airport (TYS)

  • $414 is the best price for a one-way Columbia Metropolitan Airport to Knoxville Airport flight. Return flights start at $534. These prices may change based on demand.

  • To find cheap tickets from CAE to TYS, book as early as you can. Airlines typically offer lower prices when flights are first made available.

  • Getting cheap flights from Columbia Metropolitan Airport to Knoxville Airport is easy if you can be flexible with your dates. Use the 'Whole month' search tool to see the lowest prices throughout the month and land a great deal.

  • Spend less time searching for cheap flights from CAE to TYS by creating a Price Alert. You'll get an email or notification on the app when a lower fare pops up.

  • Tailor your trip with filters. Pick your ideal departure and arrival times, airlines and total journey duration. You can also sort your results by 'Cheapest,' 'Fastest' or 'Best' flights from Columbia Metropolitan Airport to Knoxville Airport.

Handy information about Columbia Metropolitan Airport (CAE)

  • You'll find CAE at 125-A Summer Lake.

  • 81% of flights departing from Columbia Metropolitan Airport reach their destination on schedule. Given its strong on-time stats, delays are unlikely when taking off from CAE.

  • Central Columbia to Columbia Metropolitan Airport is around 19 kilometres. Depending on traffic, it'll take you about 20 minutes to get there if you're driving, catching a taxi or ride-sharing.

  • You can expect a trip time of roughly 45 minutes on public transport.

  • Get your trip off to a leisurely start by staying near CAE. Whether you've booked an early flight from Columbia Metropolitan Airport to Knoxville Airport or want to avoid feeling rushed, these stays are perfect:

Arriving at Knoxville Airport (TYS)

  • If you're coming in on a late Columbia Metropolitan Airport to Knoxville Airport flight, nothing beats the convenience of being close to the terminal. Pick up your bags from the carousel and then be tucked up in bed soon after at one of these options near TYS:

  • Grab a Knoxville Airport rental car and discover Knoxville and beyond with your own set of wheels. Budget, Alamo and Avis are top providers to choose from here.

  • Lock in the best rate by reserving your vehicle from Knoxville Airport around three weeks ahead of your trip.

Getting from Knoxville Airport (TYS) to central Knoxville

  • The street address for TYS is 2055 Alcoa Highway.

  • Knoxville Airport to central Knoxville has a drive time of about 25 minutes. It's approximately 24 kilometres away.

  • Getting to the centre by public transport will take you roughly 50 minutes.

When to fly to Knoxville Airport (TYS)

  • The quietest month for a flight from Columbia Metropolitan Airport to Knoxville Airport is March, while October is the most popular. Choose the ideal time to go to Knoxville based on whether you prefer a more fast-paced or easygoing experience.

  • Book your flight from Columbia Metropolitan Airport to Knoxville Airport for July if you want to go to Knoxville during its warmest month. You can expect temperatures of between 17ºC (63ºF) and 32ºC (90ºF).

  • January has average temperatures of between -6ºC (21ºF) and 11ºC (52ºF). Search for cheap tickets from CAE to TYS sometime around then if you like cooler conditions.

Explore more of the United States

  • Columbus is just one of the many places in the United States waiting to be discovered once you've seen Knoxville. Around 451 kilometres away to the north, top sights here include Franklin Park Conservatory and Botanical Gardens, Whetstone Park / Park of Roses and Ohio Theatre.

  • Indianapolis is another essential stop in the United States and is around 467 kilometres north-west of Knoxville. No trip is complete without seeing Lucas Oil Stadium, Eiteljorg Museum and The Children's Museum of Indianapolis.

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Plan the rest of your trip from Columbia to Knoxville

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.