$379 Cheap Flights from Knoxville (TYS) to New Orleans Louis Armstrong (MSY) in 2025

Compare flight fares from Knoxville to New Orleans Louis Armstrong

Great New Orleans Louis Armstrong flight deals, no added fees

Fly from TYS to MSY when it’s cheapest

Flight deals from Knoxville to New Orleans Louis Armstrong

Looking for a cheap last-minute deal or the best return flight from Knoxville to New Orleans Louis Armstrong? Find the lowest prices on one-way and return tickets right here.

New Orleans.$379 per passenger.Departing Thu, 24 Jul, returning Thu, 31 Jul.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Thu, 24 Jul, arriving in New Orleans Louis Armstrong.Inbound indirect flight with Delta, departs from New Orleans Louis Armstrong on Thu, 31 Jul, arriving in Knoxville.Price includes taxes and charges.From $379, select.

New Orleans.$380 per passenger.Departing Thu, 31 Jul, returning Sun, 3 Aug.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Thu, 31 Jul, arriving in New Orleans Louis Armstrong.Inbound indirect flight with Delta, departs from New Orleans Louis Armstrong on Sun, 3 Aug, arriving in Knoxville.Price includes taxes and charges.From $380, select.

New Orleans.$380 per passenger.Departing Fri, 8 Aug, returning Sun, 10 Aug.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Fri, 8 Aug, arriving in New Orleans Louis Armstrong.Inbound indirect flight with Delta, departs from New Orleans Louis Armstrong on Sun, 10 Aug, arriving in Knoxville.Price includes taxes and charges.From $380, select.

New Orleans.$463 per passenger.Departing Fri, 1 Aug, returning Sat, 25 Oct.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Fri, 1 Aug, arriving in New Orleans Louis Armstrong.Inbound indirect flight with Delta, departs from New Orleans Louis Armstrong on Sat, 25 Oct, arriving in Knoxville.Price includes taxes and charges.From $463, select.

New Orleans.$498 per passenger.Departing Sun, 24 May, returning Sat, 30 May.Return flight with United.Outbound indirect flight with United, departs from Knoxville on Sun, 24 May, arriving in New Orleans Louis Armstrong.Inbound indirect flight with United, departs from New Orleans Louis Armstrong on Sat, 30 May, arriving in Knoxville.Price includes taxes and charges.From $498, select.

New Orleans.$499 per passenger.Departing Thu, 2 Oct, returning Sun, 5 Oct.Return flight with United.Outbound indirect flight with United, departs from Knoxville on Thu, 2 Oct, arriving in New Orleans Louis Armstrong.Inbound indirect flight with United, departs from New Orleans Louis Armstrong on Sun, 5 Oct, arriving in Knoxville.Price includes taxes and charges.From $499, select.

New Orleans.$540 per passenger.Departing Sun, 21 Sep, returning Sun, 28 Sep.Return flight with United.Outbound indirect flight with United, departs from Knoxville on Sun, 21 Sep, arriving in New Orleans Louis Armstrong.Inbound indirect flight with United, departs from New Orleans Louis Armstrong on Sun, 28 Sep, arriving in Knoxville.Price includes taxes and charges.From $540, select.

New Orleans.$547 per passenger.Departing Fri, 29 Aug, returning Mon, 1 Sep.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Fri, 29 Aug, arriving in New Orleans Louis Armstrong.Inbound indirect flight with Delta, departs from New Orleans Louis Armstrong on Mon, 1 Sep, arriving in Knoxville.Price includes taxes and charges.From $547, select.

Find the cheapest month to fly from Knoxville to New Orleans Louis Armstrong

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Knoxville to New Orleans Louis Armstrong flights are currently cheapest in July.

Jul

Aug

Sep

Oct

Nov

Dec

Jan

Feb

Mar

Apr

May

Jun

Knoxville to New Orleans Louis Armstrong: Alternative routes

Compare routes from Knoxville to New Orleans below. You may find an airport to fly into that's cheaper, faster, or easier than New Orleans Louis Armstrong.

Knoxville to New Orleans: Flight information

The things to know before you go.

Cheapest flight found	$379
Cheapest month to fly	July

Finding cheap flights from Knoxville to New Orleans Louis Armstrong: Frequently asked questions

How much are return flights from Knoxville to New Orleans Louis Armstrong?

The best price we found for a return flight from Knoxville to New Orleans Louis Armstrong is $379. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Knoxville to New Orleans Louis Armstrong?

Currently, there are no airlines that fly direct from Knoxville to New Orleans Louis Armstrong. But we found flights with one or more stops from $379.

How many flights are there a week from Knoxville to New Orleans Louis Armstrong?

As of July 2025, there are no flights flying from Knoxville to New Orleans Louis Armstrong.

When is the cheapest time to fly from Knoxville to New Orleans Louis Armstrong?

The cheapest month to fly from Knoxville to New Orleans Louis Armstrong is usually July.

Which upcoming date is cheapest to fly from Knoxville Airport to New Orleans Louis Armstrong Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Knoxville Airport to New Orleans Louis Armstrong Airport on Thursday, 24 July 2025.

Can I get a direct flight from Knoxville Airport to New Orleans Louis Armstrong Airport?

No airlines currently offer direct flights between Knoxville Airport and New Orleans Louis Armstrong Airport. Most routes have one or more stops.

How can I find the best flight deal to New Orleans Louis Armstrong?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to New Orleans Louis Armstrong but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to New Orleans?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to New Orleans is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly from Knoxville Airport to New Orleans Louis Armstrong with?

Currently, Delta offers the cheapest flight tickets to New Orleans Louis Armstrong.

Flying from McGhee Tyson Airport (TYS) to Louis Armstrong New Orleans International Airport (MSY): what you need to know

New Orleans is one hour behind Knoxville and observes the UTC-5 timezone.
To ensure you catch your TYS to MSY flight, leave plenty of time for things like baggage drop and finding your gate. Turning up two hours before international departures and one hour before domestic flights is the standard rule.
During popular months like July, it's a good idea to get to the airport earlier than usual. Plan to arrive two hours before a domestic departure and four hours ahead for international flights whenever you're flying during a peak period in general.

How to find the cheapest flights from McGhee Tyson Airport (TYS) to Louis Armstrong New Orleans International Airport (MSY)

$154 is currently the best price for a one-way McGhee Tyson Airport to Louis Armstrong New Orleans International Airport flight. A return flight starts at $379. These prices can change depending on demand and availability.
Don't wait until the last moment. You're more likely to find cheap tickets from TYS to MSY if you book ahead. Airlines often offer some excellent early bird rates.
The 'Whole month' search tool shows you the cheapest flights from McGhee Tyson Airport to Louis Armstrong New Orleans International Airport across each month. It's a great way to snap up a bargain if your travel plans are flexible.
You don't need to check back in every day to find out if fares have dropped when you set up a Price Alert. We'll let you know as soon as a special offer becomes available on cheap flights from TYS to MSY.
Pick your ideal arrival and departure times, number of stops and airlines with the filters. Or sort your results by 'Cheapest' to get the best deals on flights from McGhee Tyson Airport to Louis Armstrong New Orleans International Airport.

Handy information about McGhee Tyson Airport (TYS)

You'll find TYS at 2055 Alcoa Highway.
78.98% of flights that take off from McGhee Tyson Airport touch down at their destination on time.
Central Knoxville to McGhee Tyson Airport is approximately 23 kilometres. Depending on traffic, it'll take you about 20 minutes to get there if you're ride-sharing, catching a cab or driving.
Get your holiday off to a leisurely start by staying near TYS. Whether you're boarding an early flight from McGhee Tyson Airport to Louis Armstrong New Orleans International Airport or just don't like being rushed, these stays are ideal:

Arriving at Louis Armstrong New Orleans International Airport (MSY)

The last thing you need is a lengthy trip to your hotel if you're landing late on a McGhee Tyson Airport to Louis Armstrong New Orleans International Airport flight. Reserve one of these accommodation options near MSY instead:
Follow your own route with a Louis Armstrong New Orleans International Airport rental car. Pick up a set of wheels from Budget, Dollar or Thrifty and see more of New Orleans and beyond.
Booking your ride from Louis Armstrong New Orleans International Airport around four weeks in advance boosts your odds of scoring a great price.

Getting from Louis Armstrong New Orleans International Airport (MSY) to central New Orleans

MSY is located at 900 Airline Highway.
Louis Armstrong New Orleans International Airport is approximately 24 kilometres from the centre of New Orleans. Driving there takes about 20 minutes.
Travelling to the centre on public transport takes around 50 minutes.

When to fly to Louis Armstrong New Orleans International Airport (MSY)

October is the most popular month for flights from McGhee Tyson Airport to Louis Armstrong New Orleans International Airport. To steer clear of the crowds, head to New Orleans in May.
Book your flight from McGhee Tyson Airport to Louis Armstrong New Orleans International Airport for August if you want to visit New Orleans during its warmest month. You can expect temperatures of between 25ºC (77ºF) and 36ºC (97ºF).
If you like cooler conditions, look for a cheap ticket from TYS to MSY in January. Temperatures average between 4ºC (39ºF) and 18ºC (64ºF) then.

Explore more of United States

Baton Rouge is just one of the many places in United States waiting to be discovered once you've taken in the sights of New Orleans. Around 121 kilometres away to the north-west, top sights here include Louisiana State Capitol, Louisiana's Old State Capitol and Shaw Centre for the Arts.
If you're interested in discovering another major destination in United States, consider Montgomery, roughly 451 kilometres north-east of New Orleans. Civil Rights Memorial, Rosa Parks Museum and Dexter Avenue King Memorial Baptist Church are among its highlights.