Skyscanner

Cheap Flights from Fort Myers (RSW) to San Francisco (SFO)

Compare Fort Myers Southwest Florida Reg to San Francisco International flight deals

Find the cheapest month or even day of the year to fly to San Francisco International

Book the best San Francisco International fare with no extra fees

Flight deals from Fort Myers Southwest Florida Reg to San Francisco International

Looking for a cheap last-minute deal or the best return flight from Fort Myers Southwest Florida Reg to San Francisco International? Find the lowest prices on one-way and return tickets right here.
San Francisco.$421 per passenger.Departing Sat, 27 Sep, returning Sat, 4 Oct.Return flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Fort Myers Southwest Florida Reg on Sat, 27 Sep, arriving in San Francisco International.Inbound indirect flight with Southwest Airlines, departs from San Francisco International on Sat, 4 Oct, arriving in Fort Myers Southwest Florida Reg.Price includes taxes and charges.From $421, select.
San Francisco.$422 per passenger.Departing Wed, 1 Oct, returning Wed, 8 Oct.Return flight with Delta.Outbound indirect flight with Delta, departs from Fort Myers Southwest Florida Reg on Wed, 1 Oct, arriving in San Francisco International.Inbound indirect flight with Delta, departs from San Francisco International on Wed, 8 Oct, arriving in Fort Myers Southwest Florida Reg.Price includes taxes and charges.From $422, select.
San Francisco.$461 per passenger.Departing Thu, 23 Oct, returning Sat, 1 Nov.Return flight with Delta.Outbound indirect flight with Delta, departs from Fort Myers Southwest Florida Reg on Thu, 23 Oct, arriving in San Francisco International.Inbound indirect flight with Delta, departs from San Francisco International on Sat, 1 Nov, arriving in Fort Myers Southwest Florida Reg.Price includes taxes and charges.From $461, select.
San Francisco.$467 per passenger.Departing Fri, 23 Jan, returning Thu, 19 Feb.Return flight with United.Outbound indirect flight with United, departs from Fort Myers Southwest Florida Reg on Fri, 23 Jan, arriving in San Francisco International.Inbound indirect flight with United, departs from San Francisco International on Thu, 19 Feb, arriving in Fort Myers Southwest Florida Reg.Price includes taxes and charges.From $467, select.
San Francisco.$516 per passenger.Departing Sat, 13 Sep, returning Sat, 27 Sep.Return flight with United.Outbound indirect flight with United, departs from Fort Myers Southwest Florida Reg on Sat, 13 Sep, arriving in San Francisco International.Inbound indirect flight with United, departs from San Francisco International on Sat, 27 Sep, arriving in Fort Myers Southwest Florida Reg.Price includes taxes and charges.From $516, select.
San Francisco.$539 per passenger.Departing Wed, 17 Dec, returning Wed, 24 Dec.Return flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Fort Myers Southwest Florida Reg on Wed, 17 Dec, arriving in San Francisco International.Inbound indirect flight with Southwest Airlines, departs from San Francisco International on Wed, 24 Dec, arriving in Fort Myers Southwest Florida Reg.Price includes taxes and charges.From $539, select.
San Francisco.$549 per passenger.Departing Tue, 31 Mar, returning Sat, 4 Apr.Return flight with United.Outbound indirect flight with United, departs from Fort Myers Southwest Florida Reg on Tue, 31 Mar, arriving in San Francisco International.Inbound indirect flight with United, departs from San Francisco International on Sat, 4 Apr, arriving in Fort Myers Southwest Florida Reg.Price includes taxes and charges.From $549, select.
San Francisco.$585 per passenger.Departing Mon, 20 Apr, returning Sun, 26 Apr.Return flight with Delta.Outbound indirect flight with Delta, departs from Fort Myers Southwest Florida Reg on Mon, 20 Apr, arriving in San Francisco International.Inbound indirect flight with Delta, departs from San Francisco International on Sun, 26 Apr, arriving in Fort Myers Southwest Florida Reg.Price includes taxes and charges.From $585, select.

Find the cheapest month to fly from Fort Myers Southwest Florida Reg to San Francisco International

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Fort Myers Southwest Florida Reg to San Francisco International flights are currently cheapest in October.
Sep
from $516
Oct
from $422
Nov
Find prices
Dec
from $539
Jan
Find prices
Feb
Find prices
Mar
Find prices
Apr
from $585
May
Find prices
Jun
Find prices
Jul
Find prices
Aug
Find prices

Direct flights from Fort Myers Southwest Florida Reg to San Francisco International

Fort Myers Southwest Florida Reg to San Francisco International: Alternative routes

Compare routes from Fort Myers Southwest Florida Reg to San Francisco below. You may find an airport to fly into that's cheaper, faster, or easier than San Francisco International.

Fort Myers to San Francisco: Flight information

The things to know before you go.
Cheapest flight found$421
Cheapest month to flySeptember
Average flight time6 hrs, 23 mins
Most popular airlineUnited
Average flights per week5

Finding cheap flights from Fort Myers Southwest Florida Reg to San Francisco International: Frequently asked questions

The best price we found for a return flight from Fort Myers Southwest Florida Reg to San Francisco International is $421. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
6 hours and 23 minutes is the average flight time from Fort Myers Southwest Florida Reg to San Francisco International.
United flies direct from Fort Myers Southwest Florida Reg to San Francisco International.
As of September 2025, there are 5 flights per week flying from Fort Myers Southwest Florida Reg to San Francisco International.
The cheapest month to fly from Fort Myers Southwest Florida Reg to San Francisco International is usually September.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Fort Myers Southwest Florida Reg Airport to San Francisco International Airport on Saturday, 27 September 2025.
Yes – the average flight time is 6 hours and 23 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to San Francisco International but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to San Francisco is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Southwest Airlines offers the cheapest flight tickets to San Francisco International.

Travelling from Southwest Florida International Airport (RSW) to San Francisco International Airport (SFO): what you need to know

  • San Francisco is three hours behind Fort Myers and observes the UTC-7 timezone.

  • To ensure you get on your RSW to SFO flight, allow plenty of time to check in and find your gate. Turning up two hours before international departures and one hour before domestic flights is the general travel rule.

  • During popular months like October, you'll want to get to the airport even earlier. Plan to arrive two hours before a domestic departure and four hours ahead for an international flight whenever you're travelling during peak periods in general.

  • Think about adding a stopover when booking your ticket from Southwest Florida International Airport to San Francisco International Airport. Simply uncheck 'Direct flights only' to break up your journey, or perhaps explore a new destination along the way. Here are some options between RSW and SFO:

    • George Bush Intercontinental Airport

    • Dallas/Fort Worth International Airport

    • Hartsfield-Jackson Atlanta International Airport

How to find the cheapest flights from Southwest Florida International Airport (RSW) to San Francisco International Airport (SFO)

  • The cheapest price we've found for a one-way Southwest Florida International Airport to San Francisco International Airport flight is $211. A round-trip plane ticket is currently $421. Depending on the availability when you book, these fares can change.

  • Don't wait until the last moment. You're more likely to find cheap tickets from RSW to SFO if you book in advance. Airlines often have some amazing early bird rates.

  • If you're willing to be flexible with your travel dates, try using the 'Whole month' tool. It'll show you the cheapest price across every month when looking for your flight from Southwest Florida International Airport to San Francisco International Airport.

  • Snapping up cheap flights from RSW to SFO is a cinch with Price Alerts. All you need to do is create one of these automatic alerts and we'll get in touch when a lower fare pops up.

  • Tailor your trip with filters. Select your preferred arrival and departure times, airlines and total journey duration. You can also sort your results by 'Best,' 'Fastest' or 'Cheapest' flights from Southwest Florida International Airport to San Francisco International Airport.

Handy information about Southwest Florida International Airport (RSW)

  • RSW is located at 11000 Terminal Access Road.

  • Of all flights leaving Southwest Florida International Airport, 77.32% arrive on time at their destination.

  • To reach Southwest Florida International Airport from central Fort Myers, it'll take around 25 minutes by car. Of course, this depends on traffic conditions. It's approximately 23 kilometres from the airport to the city centre.

  • Searching for a convenient hotel near RSW? If you're catching an early flight from Southwest Florida International Airport to San Francisco International Airport, these accommodation options will have you moments from your departure lounge:

Arriving at San Francisco International Airport (SFO)

Getting from San Francisco International Airport (SFO) to central San Francisco

  • From San Francisco International Airport, San Francisco is approximately 21 kilometres away. It takes around 20 minutes to drive to the centre.

  • Getting there by public transport will take you around 45 minutes.

When to fly to San Francisco International Airport (SFO)

  • The quietest month for a flight from Southwest Florida International Airport to San Francisco International Airport is February, while August is the busiest. Choose the ideal time to go to San Francisco based on whether you prefer a more fast-paced or easygoing experience.

  • Lock in your flight from Southwest Florida International Airport to San Francisco International Airport for September if you want to visit San Francisco during its warmest month. Expect temperatures of between 12ºC (54ºF) and 22ºC (72ºF).

  • Look for cheap tickets from RSW to SFO in January if you like cooler conditions. Temperatures are at their lowest then, ranging between 6ºC (43ºF) and 16ºC (61ºF) on average.

Explore more of United States

  • You've seen San Francisco, now it's time to discover more of United States. Travel about 64 kilometres south-east to San Jose to tick off its top attractions. From Winchester Mystery House to Rosicrucian Egyptian Museum and San Jose Museum of Art, there's plenty to keep you on the go.

  • Around 257 kilometres south-east of San Francisco, Fresno is another favourite stop in United States. Get a taste of what this destination has to offer at Forestiere Underground Gardens, Fresno Chaffee Zoo and Shinzen Japanese Garden.

More travel options

Plan the rest of your trip from Fort Myers to San Francisco

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.