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Cheap Flights from Panama City (PTYA) to Madrid (MAD)

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Compare Panama City to Madrid flight deals

Find the cheapest month or even day of the year to fly to Madrid

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Flight deals from Panama City to Madrid

Looking for a cheap last-minute deal or the best return flight from Panama City to Madrid? Find the lowest prices on one-way and return tickets right here.
Madrid.$1,079 per passenger.Departing Mon, 8 Sep, returning Sat, 4 Oct.Return flight with Air France.Outbound indirect flight with Air France, departs from Panama City Tocumen International on Mon, 8 Sep, arriving in Madrid.Inbound indirect flight with Air France, departs from Madrid on Sat, 4 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,079, select.
Madrid.$1,079 per passenger.Departing Thu, 24 Jul, returning Mon, 18 Aug.Return flight with KLM.Outbound indirect flight with KLM, departs from Panama City Tocumen International on Thu, 24 Jul, arriving in Madrid.Inbound indirect flight with KLM, departs from Madrid on Mon, 18 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,079, select.
Madrid.$1,079 per passenger.Departing Sun, 29 Jun, returning Wed, 3 Sep.Return flight with Air France and KLM.Outbound indirect flight with Air France, departs from Panama City Tocumen International on Sun, 29 Jun, arriving in Madrid.Inbound indirect flight with KLM, departs from Madrid on Wed, 3 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,079, select.
Madrid.$1,079 per passenger.Departing Sat, 12 Jul, returning Sat, 11 Oct.Return flight with KLM and Air France.Outbound indirect flight with KLM, departs from Panama City Tocumen International on Sat, 12 Jul, arriving in Madrid.Inbound indirect flight with Air France, departs from Madrid on Sat, 11 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,079, select.
Madrid.$1,079 per passenger.Departing Sat, 5 Jul, returning Mon, 1 Sep.Return flight with KLM and Air France.Outbound indirect flight with KLM, departs from Panama City Tocumen International on Sat, 5 Jul, arriving in Madrid.Inbound indirect flight with Air France, departs from Madrid on Mon, 1 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,079, select.
Madrid.$1,079 per passenger.Departing Mon, 2 Jun, returning Tue, 10 Jun.Return flight with Air France.Outbound indirect flight with Air France, departs from Panama City Tocumen International on Mon, 2 Jun, arriving in Madrid.Inbound indirect flight with Air France, departs from Madrid on Tue, 10 Jun, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,079, select.
Madrid.$1,090 per passenger.Departing Mon, 15 Sep, returning Mon, 29 Sep.Return flight with Air France.Outbound indirect flight with Air France, departs from Panama City Tocumen International on Mon, 15 Sep, arriving in Madrid.Inbound indirect flight with Air France, departs from Madrid on Mon, 29 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,090, select.
Madrid.$1,102 per passenger.Departing Thu, 29 May, returning Tue, 10 Jun.Return flight with Air France.Outbound indirect flight with Air France, departs from Panama City Tocumen International on Thu, 29 May, arriving in Madrid.Inbound indirect flight with Air France, departs from Madrid on Tue, 10 Jun, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,102, select.

Find the cheapest month to fly from Panama City to Madrid

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Madrid flights are currently cheapest in June.
May
from $1,129
Jun
from $1,079
Jul
from $1,123
Aug
from $1,102
Sep
from $1,090
Oct
from $1,114
Nov
from $1,114
Dec
from $1,187
Jan
from $1,129
Feb
from $1,120
Mar
from $1,122
Apr
from $1,129

Direct flights from Panama City to Madrid

Panama City to Madrid: Alternative routes

Compare routes from Panama City to Madrid below. You may find an airport to fly into that's cheaper, faster, or easier than Madrid.

Panama City to Madrid: Flight information

The things to know before you go.
Cheapest flight found$1,079
Cheapest month to flyJuly
Average flight time9 hrs, 59 mins
Most popular airlineCopa
Average flights per week48

Finding cheap flights from Panama City to Madrid: Frequently asked questions

The best price we found for a return flight from Panama City to Madrid is $1,079. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
9 hours and 59 minutes is the average flight time from Panama City to Madrid.
Copa, Etihad Airways and Air Europa fly direct from Panama City to Madrid.
As of May 2025, there are 52 flights per week flying from Panama City to Madrid.
The cheapest month to fly from Panama City to Madrid is usually May 2025.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Madrid Airport on Thursday, 24 July 2025.
Yes – the average flight time is 9 hours and 59 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Madrid but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Madrid is around 40 days in advance, so don’t leave your flight to the last minute.

Flying from Panama City to Adolfo Suarez Madrid-Barajas Airport (MAD): what you need to know

  • There are two main airports you can fly out of in Panama City. Explore your options departing from Tocumen International Airport (PTY) or Panama Pacifico Airport (BLB) when planning your flight from Panama City to Adolfo Suarez Madrid-Barajas Airport (MAD).

  • The average time for a direct flight from Panama City to Adolfo Suarez Madrid-Barajas Airport is 9 hours 57 minutes.

  • Madrid is 6 hours ahead of Panama City. Adolfo Suarez Madrid-Barajas Airport is located in Madrid, which operates on the UTC+1 timezone.

  • Tocumen International Airport (PTY) to Adolfo Suarez Madrid-Barajas Airport (MAD) is the most popular route. There are 32 direct weekly departures to choose from. If you have things to do before heading off, take the last flight with Air Europa at 21:30. Choose the first PTY to MAD departure with Iberia at 17:10 if you want to get going earlier.

  • Arriving two hours before an international flight and one hour ahead of a domestic departure are golden rules for stress-free travel. Be at the airport on time to board your flight from Panama City to MAD.

  • During popular months such as June, it's a good idea to get to the airport earlier. Plan to arrive two hours before domestic departures and four hours ahead of an international flight whenever you're travelling during high season in general.

Airports in Panama City

Tocumen International Airport (PTY)

  • Tocumen International Airport (PTY) provides a hassle-free way to reach your destination. Nonstop flights from Panama City to Adolfo Suarez Madrid-Barajas Airport (MAD) operate out of this terminal.

  • Air Europa is a well-known carrier that operates direct flights from Panama City to Adolfo Suarez Madrid-Barajas Airport taking off from PTY.

  • Think about adding a stopover to potentially save money on your flight from Panama City to MAD. Simply deselect 'Direct flights only' when searching for departures from Tocumen International Airport (PTY). Take a break from travelling at one of these airports:

    • Miami International Airport (MIA)

    • El Dorado International Airport (BOG)

    • Las Americas International Airport (SDQ)

  • The distance from central Panama City to PTY is roughly 21 kilometres. Use Google Maps for the quickest way to get there, whether you plan to drive or take public transport.

  • Need a handy hotel close to Tocumen International Airport? If you've booked an early flight from Panama City to Adolfo Suarez Madrid-Barajas Airport, these accommodation options will put you moments from your departure lounge:

Panama Pacifico Airport (BLB)

  • Planning to leave from Panama Pacifico Airport (BLB)? You can book a direct flight from Panama City to Adolfo Suarez Madrid-Barajas Airport (MAD) departing from this hub.

  • Consider adding a stop at El Dorado International Airport (BOG). It's a key stopover on a flight from Panama City to Adolfo Suarez Madrid-Barajas Airport (MAD) leaving Panama Pacifico Airport. Use a long layover to explore nearby, or take advantage of a short break to grab a coffee at an airport cafe.

  • BLB is approximately 16 kilometres from central Panama City. It'll take you 22 minutes or so to reach the airport driving from the city centre.

  • You're going on holiday, so why not enjoy an extra night away from home? Think about checking in to one of these accommodation options near Panama Pacifico Airport the day before your flight from Panama City to MAD:

About Adolfo Suarez Madrid-Barajas Airport (MAD)

  • If you're arriving on a late flight from Panama City to Adolfo Suarez Madrid-Barajas Airport, few things top the convenience of staying near the terminal. Grab your luggage from the carousel and then be showered and resting soon after at one of these options near MAD:

Getting from Adolfo Suarez Madrid-Barajas Airport (MAD) to central Madrid

  • Adolfo Suarez Madrid-Barajas Airport to central Madrid takes about 26 minutes by car. It's approximately 18 kilometres away. Discover what options are available, such as car rentals, cabs or ride-sharing.

  • Getting to the centre by public transport takes roughly 37 minutes.

How to find the cheapest flights from Panama City to Adolfo Suarez Madrid-Barajas Airport (MAD)

  • $666 is the lowest price we've seen for a one-way ticket from Panama City to Adolfo Suarez Madrid-Barajas Airport. Return flights start from $1,079. Prices may vary depending on availability at the time of booking.

  • To snag flight tickets from Panama City to MAD, book your journey 8 months ahead of your planned departure.

  • You'll snag the best savings on your tickets from Panama City to Adolfo Suarez Madrid-Barajas Airport if you take off in May. Go one step further and use the 'Whole month' tool to find the cheapest day to fly.

  • Set up a Price Alert and track any changes on this route through email or push notifications. You'll be the first to know when the fares drop. Timing is key for finding flight tickets from Panama City to MAD.

  • Tailor your flights with filters. Pick your departure and arrival times, airlines and total journey duration. You can also sort your results by 'Fastest,' 'Best' or 'Cheapest' flights from Panama City to Adolfo Suarez Madrid-Barajas Airport.

The best time to fly from Panama City to Adolfo Suarez Madrid-Barajas Airport (MAD)

  • April is the quietest time to fly to Madrid. Alternatively, join the crowds and take off in July. This is the most popular month for flights from Panama City to Adolfo Suarez Madrid-Barajas Airport, but the best time to go is up to you.

  • Think about the type of weather that'll suit your plans for Madrid. The warmest month is July. Lock in your flights from Panama City to MAD during then and you can expect temperatures of between 17ºC and 36ºC.

  • Look for cheap flights from Panama City to Adolfo Suarez Madrid-Barajas Airport in January if you want to travel in cooler conditions. Temperatures are at their lowest around then, ranging between 0ºC and 11ºC on average.

More about Madrid

  • When it comes to searching for somewhere to lay your head, you'll find the most popular stays in Madrid right here. Check out these options once you've booked your flight from Panama City to Adolfo Suarez Madrid-Barajas Airport:

  • One of the best ways to get a feel for Madrid is to visit its leading attractions. Essential stops include El Retiro Park, Puerta del Sol and Plaza Mayor.

Complete your Madrid trip with a car rental

  • Hop behind the wheel of one of our car rentals in Madrid and explore on your own terms. Easily compare prices from trusted rental companies in one place after booking your hotel and cheap flights from Panama City to Adolfo Suarez Madrid-Barajas Airport.

Plan the rest of your trip from Panama City to Madrid

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.