Cheap Flights from Panama City (PTY) to Istanbul (IST)

Compare Panama City Tocumen International to Istanbul flight deals

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Flight deals from Panama City Tocumen International to Istanbul

Looking for a cheap last-minute deal or the best return flight from Panama City Tocumen International to Istanbul? Find the lowest prices on one-way and return tickets right here.

Istanbul.$1,539 per passenger.Departing Sun, 8 Mar, returning Wed, 18 Mar.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Sun, 8 Mar, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Wed, 18 Mar, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,539, select.

Istanbul.$1,540 per passenger.Departing Fri, 27 Jun, returning Wed, 10 Sep.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Fri, 27 Jun, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Wed, 10 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,540, select.

Istanbul.$1,547 per passenger.Departing Fri, 7 Nov, returning Mon, 17 Nov.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Fri, 7 Nov, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Mon, 17 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,547, select.

Istanbul.$1,547 per passenger.Departing Sat, 28 Jun, returning Thu, 28 Aug.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Sat, 28 Jun, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Thu, 28 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,547, select.

Istanbul.$1,601 per passenger.Departing Fri, 19 Sep, returning Fri, 10 Oct.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Fri, 19 Sep, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Fri, 10 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,601, select.

Istanbul.$1,659 per passenger.Departing Wed, 11 Jun, returning Wed, 18 Jun.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Wed, 11 Jun, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Wed, 18 Jun, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,659, select.

Istanbul.$1,663 per passenger.Departing Tue, 20 Jan, returning Mon, 26 Jan.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Tue, 20 Jan, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Mon, 26 Jan, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,663, select.

Istanbul.$1,838 per passenger.Departing Wed, 20 Aug, returning Wed, 27 Aug.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Wed, 20 Aug, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Wed, 27 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,838, select.

Find the cheapest month to fly from Panama City Tocumen International to Istanbul

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City Tocumen International to Istanbul flights are currently cheapest in March.

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Direct flights from Panama City Tocumen International to Istanbul

Panama City Tocumen International to Istanbul: Alternative routes

Compare routes from Panama City Tocumen International to Istanbul below. You may find an airport to fly into that's cheaper, faster, or easier than Istanbul.

Panama City to Istanbul: Flight information

The things to know before you go.

Cheapest flight found	$1,539
Cheapest month to fly	March
Average flight time	12 hrs, 50 mins
Most popular airline	Turkish Airlines
Average flights per week	20

Finding cheap flights from Panama City Tocumen International to Istanbul: Frequently asked questions

How much are return flights from Panama City Tocumen International to Istanbul?

The best price we found for a return flight from Panama City Tocumen International to Istanbul is $1,539. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

How long does it take to fly from Panama City Tocumen International to Istanbul?

12 hours and 50 minutes is the average flight time from Panama City Tocumen International to Istanbul.

Which airlines fly direct from Panama City Tocumen International to Istanbul?

Turkish Airlines and Copa fly direct from Panama City Tocumen International to Istanbul.

How many flights are there a week from Panama City Tocumen International to Istanbul?

As of May 2025, there are 20 flights per week flying from Panama City Tocumen International to Istanbul.

When is the cheapest time to fly from Panama City Tocumen International to Istanbul?

The cheapest month to fly from Panama City Tocumen International to Istanbul is usually May 2025.

Which upcoming date is cheapest to fly from Panama City Tocumen International Airport to Istanbul Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Panama City Tocumen International Airport to Istanbul Airport on Sunday, 8 March 2026.

Can I get a direct flight from Panama City Tocumen International Airport to Istanbul Airport?

Yes – the average flight time is 12 hours and 50 minutes.

How can I find the best flight deal to Istanbul?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Istanbul but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Istanbul?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Istanbul is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly from Panama City Tocumen International Airport to Istanbul with?

Currently, Air Europa and Turkish Airlines offer the cheapest flight tickets to Istanbul.

Travelling from Tocumen International Airport (PTY) to Istanbul Ataturk Airport (IST): what you need to know

Around 12 hours 50 minutes is how long you'll be travelling on a direct flight from Tocumen International Airport to Istanbul Ataturk Airport.
Istanbul's timezone is UTC+3, which makes Istanbul eight hours ahead of Panama City.
You can choose from 15 weekly Tocumen International Airport to Istanbul Ataturk Airport flights. The 19:05 departure with Turkish Airlines is the earliest flight available. Turkish Airlines operates the latest service of the day at 21:50.
Give yourself enough time to catch your PTY to IST flight. It's generally best to arrive two hours before international departures and an hour ahead for domestic flights.
During popular months like June, it's a good idea to get to the airport earlier than usual. Arrive two hours before domestic departures and four hours ahead of an international flight whenever you're travelling during a peak period in general.
Turkish Airlines offers direct flights from Tocumen International Airport to Istanbul Ataturk Airport. Book with this popular carrier, then get ready to check out the sights in Istanbul — and maybe even more of Türkiye (Turkey) if your schedule allows.
The airline most travellers prefer to fly with on this route is Turkish Airlines.
Think about adding a stopover when booking your ticket from Tocumen International Airport to Istanbul Ataturk Airport. Simply uncheck 'Direct flights only' to break up your trip, or enjoy a detour to a new and interesting place. Here's where you can stop between PTY and IST:
- Adolfo Suarez Madrid-Barajas Airport
- Washington Dulles International Airport
- Hartsfield-Jackson Atlanta International Airport

How to find the cheapest flights from Tocumen International Airport (PTY) to Istanbul Ataturk Airport (IST)

$943 is currently the best price for a one-way Tocumen International Airport to Istanbul Ataturk Airport flight. Return flights start from $1,539. These fares can change depending on demand.
To get cheap tickets from PTY to IST, reserve your journey eight months before your departure date.
The cheapest month for flights from Tocumen International Airport to Istanbul Ataturk Airport is July. Use the 'Whole month' tool to see the lowest airfares if you have flexible travel dates.
There's no need to check back in every day to find out if fares have dropped when you set up a Price Alert. We'll update you as soon as a special offer becomes available on cheap flights from PTY to IST.
Lock in the ideal flight for you by using the filters. To see the 'Cheapest,' 'Fastest' or 'Best' flights from Tocumen International Airport to Istanbul Ataturk Airport, use the 'Sort by' tool. You can also filter by arrival and departure times, airline, and journey duration.

Handy information about Tocumen International Airport (PTY)

Tocumen International Airport has a strong on-time performance, reducing the likelihood of delays. Departures from PTY arrive at their destination as scheduled 86.03% of the time.
Central Panama City to Tocumen International Airport is approximately 21 kilometres. Depending on traffic, it'll take about 20 minutes to get there if you're driving, ride-sharing or catching a cab.
Planning to take public transport? You can expect a journey time of around 1 hour 5 minutes.
Booked an early flight from Tocumen International Airport to Istanbul Ataturk Airport? Avoid rushing to the airport (and catch some extra z's) by choosing one of these stays close to PTY:

Arriving at Istanbul Ataturk Airport (IST)

Consider staying in a hotel close to IST if you have a late Tocumen International Airport to Istanbul Ataturk Airport flight. Pick one of these options and skip the long transfer after landing:
Begin your adventure by picking up an Istanbul Ataturk Airport rental car. Grab your wheels from Hit, Avec car rentals or Eren Rent a Car and explore beyond Istanbul's usual tourist stops.
To lock in the lowest price, reserve your ride from Istanbul Ataturk Airport around two weeks in advance.

Getting from Istanbul Ataturk Airport (IST) to central Istanbul

From Istanbul Ataturk Airport, Istanbul is approximately 48 kilometres away. It takes around 50 minutes to reach the centre by car.
It takes around 1 hour 45 minutes if you're using public transport.

When to fly to Istanbul Ataturk Airport (IST)

April is the most popular month for flights from Tocumen International Airport to Istanbul Ataturk Airport. To skip the crowds, go to Istanbul in February.
The warmest month in Istanbul is August, with temperatures ranging between 20ºC (68ºF) and 30ºC (86ºF). Book your flights from Tocumen International Airport to Istanbul Ataturk Airport in this month if this is the type of weather you like.
January has average temperatures of between 2ºC (36ºF) and 11ºC (52ºF). Look for cheap tickets from PTY to IST around that time if you want to travel in cooler conditions.

Explore more of Türkiye (Turkey)

Ankara is just one of the many cities in Türkiye (Turkey) waiting to be discovered once you've taken in the sights of Istanbul. Around 354 kilometres away to the east, well-known attractions include Museum of Anatolian Civilizations, Kocatepe Mosque (Kocatepe Camii) and Genclik Park.
If there's time to check out another major stop in Türkiye (Turkey), head for Izmir, roughly 322 kilometres south-west of Istanbul. Kordonboyu, Kadifekale Castle and Konak Square are among the biggest draws.