$1,143 Cheap Flights from Prague (PRG) to Panama City (PTYA) in 2025

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Flight deals from Prague to Panama City

Looking for a cheap last-minute deal or the best return flight from Prague to Panama City? Find the lowest prices on one-way and return tickets right here.

Panama City.$1,143 per passenger.Departing Wed, 17 Sep, returning Mon, 29 Sep.Return flight with Condor.Outbound indirect flight with Condor, departs from Prague on Wed, 17 Sep, arriving in Panama City Tocumen International.Inbound indirect flight with Condor, departs from Panama City Tocumen International on Mon, 29 Sep, arriving in Prague.Price includes taxes and charges.From $1,143, select.

Panama City.$1,221 per passenger.Departing Mon, 9 Feb, returning Wed, 18 Feb.Return flight with Vueling Airlines and Avianca.Outbound indirect flight with Vueling Airlines, departs from Prague on Mon, 9 Feb, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Wed, 18 Feb, arriving in Prague.Price includes taxes and charges.From $1,221, select.

Panama City.$1,232 per passenger.Departing Sun, 20 Jul, returning Mon, 28 Jul.Return flight with Condor.Outbound indirect flight with Condor, departs from Prague on Sun, 20 Jul, arriving in Panama City Tocumen International.Inbound indirect flight with Condor, departs from Panama City Tocumen International on Mon, 28 Jul, arriving in Prague.Price includes taxes and charges.From $1,232, select.

Panama City.$1,268 per passenger.Departing Wed, 1 Oct, returning Mon, 13 Oct.Return flight with Condor.Outbound indirect flight with Condor, departs from Prague on Wed, 1 Oct, arriving in Panama City Tocumen International.Inbound indirect flight with Condor, departs from Panama City Tocumen International on Mon, 13 Oct, arriving in Prague.Price includes taxes and charges.From $1,268, select.

Panama City.$1,429 per passenger.Departing Sun, 15 Feb, returning Mon, 2 Mar.Return flight with Vueling Airlines and Iberia.Outbound indirect flight with Vueling Airlines, departs from Prague on Sun, 15 Feb, arriving in Panama City Tocumen International.Inbound indirect flight with Iberia, departs from Panama City Tocumen International on Mon, 2 Mar, arriving in Prague.Price includes taxes and charges.From $1,429, select.

Panama City.$1,442 per passenger.Departing Sat, 7 Mar, returning Sun, 29 Mar.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Prague on Sat, 7 Mar, arriving in Panama City Tocumen International.Inbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Sun, 29 Mar, arriving in Prague.Price includes taxes and charges.From $1,442, select.

Panama City.$1,443 per passenger.Departing Wed, 19 Nov, returning Wed, 26 Nov.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Prague on Wed, 19 Nov, arriving in Panama City Tocumen International.Inbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Wed, 26 Nov, arriving in Prague.Price includes taxes and charges.From $1,443, select.

Panama City.$1,444 per passenger.Departing Fri, 19 Sep, returning Fri, 3 Oct.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Prague on Fri, 19 Sep, arriving in Panama City Tocumen International.Inbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Fri, 3 Oct, arriving in Prague.Price includes taxes and charges.From $1,444, select.

Find the cheapest month to fly from Prague to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Prague to Panama City flights are currently cheapest in September.

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Alternative Prague to Panama City routes

Looking for the cheapest, fastest or easiest route from Prague to Panama City? You could fly into the following airports instead.

Prague to Panama City: Flight information

The things to know before you go.

Cheapest flight found	$1,143
Cheapest month to fly	September

Finding cheap flights from Prague to Panama City: Frequently asked questions

How many airports are there in Panama City?

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.

How much are return flights from Prague to Panama City?

The best price we found for a return flight from Prague to Panama City is $1,143. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Prague to Panama City?

Currently, there are no airlines that fly direct from Prague to Panama City. But we found flights with one or more stops from $1,143.

How many flights are there a week from Prague to Panama City?

As of July 2025, there are no flights flying from Prague to Panama City.

When is the cheapest time to fly from Prague to Panama City?

The cheapest month to fly from Prague to Panama City is usually September.

Which is the cheapest airport to fly into in Panama City?

If you're flying from Prague Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from $1,143.

Which upcoming date is cheapest to fly from Prague Airport to Panama City on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Prague Airport to Panama City on Wednesday, 17 September 2025.

Can I get a direct flight from Prague Airport to Panama City?

No airlines currently offer direct flights between Prague Airport and Panama City. Most routes have one or more stops.

How can I get the best flight deal from Prague Airport to Panama City?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Panama City?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.

What’s the weather like in Panama City?

In July, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.

Which is the cheapest airline to fly from Prague Airport to Panama City with?

Currently, Condor offers the cheapest flight tickets to Panama City.

Travelling from Vaclav Havel Airport Prague (PRG) to Panama City: what you need to know

Vaclav Havel Airport Prague is located in Prague. Based in the UTC-5 timezone, Panama City is six hours behind Prague.
Give yourself enough time to get on your PRG to Panama City flight. As a general rule, arrive two hours before international departures and an hour ahead for domestic flights.
Longer lines at check-in and security are likely if you're flying during high season, so allow some extra breathing room. A good general rule for peak periods? Get there up to four hours ahead for international flights and at least two hours for domestic departures.
A stopover is the ideal opportunity to break up your journey and possibly even explore another city. When searching for flight tickets from PRG to Panama City, deselect the 'Direct flights only' box to see where you can stop along the way. Consider one of these popular options:
- Amsterdam Airport Schiphol (AMS)
- Charles de Gaulle Airport (CDG)
- Adolfo Suarez Madrid-Barajas Airport (MAD)
Travelling from central Prague to PRG takes around 50 minutes on public transport. If you ride-share, drive or take a cab, you'll cover the 13 kilometres in 30 minutes or so, depending on traffic.
In search of a hotel near PRG? If you're catching an early flight from Vaclav Havel Airport Prague to Panama City, these stays will get you from your pillow to the plane in no time:
When it comes to the on-time performance of Vaclav Havel Airport Prague, 69.89% of flights complete their journey on time.

How to find the cheapest flights from Vaclav Havel Airport Prague (PRG) to Panama City

The best price we've seen for a one-way Vaclav Havel Airport Prague to Panama City flight is $624. The cheapest price for a return flight is $1,143. Remember fares may change due to availability at the time of booking.
Booking ahead of time is often the key to scoring a cheap flight from PRG to Panama City. Fares tend to rise as seats fill up, so the closer you get to departure, the more you'll likely pay.
Landing cheap tickets from Vaclav Havel Airport Prague to Panama City is easier if you can be flexible with your travel dates. Try using the 'Whole month' search function to access the best prices across the month and score a sweet deal.
There's no need to check back constantly to see if fares have dropped when you set up a Price Alert. We'll update you as soon as there's an even bigger deal on cheap flights from PRG to Panama City.
Save money on your flight from Vaclav Havel Airport Prague to Panama City with the help of our filters. Choose your ideal times, airlines and number of stops, then sort the results by 'Cheapest' for the best deals.

Airports in Panama City

Tocumen International Airport (PTY)

Tocumen International Airport (PTY) to central Panama City takes around 20 minutes by car. The centre is roughly 21 kilometres away.
When travelling by public transport, expect a journey time of around 1 hour 5 minutes.
If you're arriving on a late flight from Vaclav Havel Airport Prague to Panama City, nothing beats the convenience of staying near the terminal. Collect your bags from the carousel and then be showered and snoozing not long after at one of these accommodation options near PTY:
Grab a Tocumen International Airport rental car and discover Panama City and beyond with your own set of wheels. Avis, Dollar and MEX are popular outlets to choose from here.
Lock in the best possible rate by reserving your vehicle from Tocumen International Airport around three weeks ahead of your flight from PRG to Panama City.

Marcos A. Gelabert International Airport (PAC)

After your flight from Vaclav Havel Airport Prague to Panama City has touched down, you can get to the city centre in around 5 minutes by car. Central Panama City is roughly 2 kilometres from Marcos A. Gelabert International Airport (PAC).
You can expect the journey to take about 25 minutes on public transport.
There are some great places to drop your things at near PAC. Kick back and get cosy after your PRG to Panama City flight at one of these perfectly located options:
The quickest way to reach your destination is with a Marcos A. Gelabert International Airport rental car. Grab a set of wheels from Thrifty, Avis or Alamo and get going in the blink of an eye.
Call dibs on the best options. Securing your ride from PAC three weeks ahead of time often means better deals and a greater range of vehicles.

Panama Pacifico Airport (BLB)

Panama Pacifico Airport (BLB) is around 16 kilometres from central Panama City. It takes about 20 minutes to reach the city centre in a cab or ride-share once you've stepped off your flight from Vaclav Havel Airport Prague to Panama City.
Reserve a hotel near BLB and go from landing to lounging in your room in a flash. Whether you're arriving on a late PRG to Panama City flight or just want to keep your travel plans simple, these stays will have you settling in quickly:
Start your travels without worrying about how to reach your destination with a Panama Pacifico Airport rental car. You can book with reliable companies here like Sixt, Dollar and Thrifty.
Plan ahead and put that extra money in your pocket. Book your ride from BLB one week before your flight from Vaclav Havel Airport Prague to Panama City to access the best deals.

Best time to go to Panama City

Carefully consider your trip dates before locking in your flight from Vaclav Havel Airport Prague to Panama City. The city comes alive in high season, but rates are usually higher and major attractions can get busy. Visit Panama City in low season if you prefer a quieter vibe.
When booking your Vaclav Havel Airport Prague to Panama City flight ticket, think about the kind of weather you prefer. March is the warmest month in Panama City, with temperatures ranging from 21ºC (70ºF) to 32ºC (90ºF).
February sees average temperatures of between 22ºC (72ºF) and 31ºC (88ºF). Look for a cheap ticket from PRG to Panama City around that time if you like travelling in cooler conditions.

More about Panama City

Start your Panama City trip off on the right foot by choosing the ideal place to stay. After booking your flight from Vaclav Havel Airport Prague to Panama City, check out our selection of accommodation options including:
Casco Viejo and Panama Canal Museum are a couple of big attractions to add to your Panama City travel itinerary. Keep the momentum going by heading to Cinta Costera.

Explore more of Panama

David is just one of the many places in Panama waiting to be discovered after you've experienced Panama City. Around 322 kilometres away to the west, popular attractions include Parque Cervantes, Altos del Rio Park and Coquito Hills Park.
If you're ready to explore another side of Panama, consider Santiago de Veraguas, about 193 kilometres south-west of Panama City. Santiago the Apostle Cathedral, Santiago de Veraguas, The Church of Jesus Christ of Latter Day Saints and La Placita San Juan De Dios are key highlights.