Hotels by Comfort Inn in Rochester

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Prices may change – pop in your dates for the best estimate. Note that prices are based on previous traveller searches and partner prices.
Prices may change – pop in your dates for the best estimate. Note that prices are based on previous traveller searches and partner prices.
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Fast facts

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Number of hotels by Comfort Inn in Rochester2
Best price foundComfort Inn & Suites West - Medical Center, $116
Most popular hotel by Comfort InnComfort Inn & Suites West - Medical Center, from $116
Highest rated hotel by Comfort InnComfort Inn & Suites Rochester South Mayo Clinic, from $122
Average price$116
Cheapest monthApril

Finding your ideal Rochester hotel by Comfort Inn: FAQs

In Rochester, the expected average temperature in February is -7°C. The warmest month is typically July, which averages 27°C. The coolest month is January, with temperatures averaging -15°C. The rainiest month is June, and the driest month is January.
Lots of hotels offer amendable booking options or free cancellation within a certain time frame leading up to your stay. You might find Comfort Inn deals in Rochester that offer this kind of flexibility when you search using Skyscanner.
Yes – a lot of larger hotels reduce their room rates if there are still plenty of rooms left in order to sell them. Willing to take the gamble? It could be possible that Comfort Inn rates in Rochester will decrease a little in the days leading up to your trip.
It’s no secret that savvy travellers often avoid weekends to beat the crowds and inflated flight or train prices. When it comes to rooms rates for hotels by Comfort Inn in Rochester, it looks they're around $124 on Friday, Saturday and Sunday nights, compared to $121 during the week.
If you want to bag the cheapest room, try booking a city hotel by Comfort Inn on a Thursday - this is when prices trend the lowest.
We crunched all the pricing data we could find across the net, and it looks like the cheapest month to book a hotel by Comfort Inn in Rochester is April, with an average price of $122 per night. The most expensive month is September, when the average room rate can rise to $147.
The lowest room rate for Comfort Inn hotels in Rochester we found this upcoming weekend is the Comfort Inn & Suites West - Medical Center for $117. And for the weekend after that (21 February 2026), it looks like the Comfort Inn & Suites West - Medical Center has room rates as low as $118.